7.7 Cancer Therapy and Alternative Gene Therapy Part 2 Flashcards
1
Q
What is a benefit of epigentic therapies compared to gene therapies?
A
they would be reversible
2
Q
What is the general function of epigenetic therapies?
A
drugs that will reprogram gene expression by modifying chromatin remodeling or controlling DNA methylation
3
Q
What is an example of an epigentic drug that has been approved by the FDA?
A
azacytidine (vidaza)
4
Q
What is Vidaza used to treat?
A
leukemia and its precursors
5
Q
What is the general function of Vidaza?
A
mimics cytidine and incorporates into growing DNA strand where it irreversibly binds methylation enzymes preventing hypermethylation of DNA sites
