3.4 Cell Division Part 4 Flashcards

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1
Q

What are cdc mutations?

A

cell division cycle mutations

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2
Q

Which genes are commonly mutated?

A

kinases

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3
Q

What are kinases needed for?

A

phosphorylation of proteins involved in cell signaling and metabolic pathways

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4
Q

How are most kinases found in a cell?

A

down regulated state

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5
Q

What activates kinases?

A

cyclins

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6
Q

What are the main functions of cell cycle checkpoints

A

monitor the mitotic process to ensure things are going smoothly before proceeding to the next stage

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7
Q

What is the main difference between mitosis and meiosis?

A

mitosis has a lack of genetic variation while meiosis has a lot of genetic diversity

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8
Q

What is crossing over?

A

exchange of genetic information between homologous chromosomes

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9
Q

What is the first stage of meiosis?

A

prophase I

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10
Q

What occurs during prophase I?

A

homologous chromosomes undergo synapsis

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11
Q

What is synapsis?

A

homologous chromosomes pairing up

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12
Q

What occurs during synapsis?

A

chromosomes are so close together they undergo crossover events

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13
Q

What is a bivalent?

A

synapsed pair of chromosomes

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14
Q

What is the bivalent number equal to?

A

the haploid number

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15
Q

What is a tetrad?

A

bivalents that have condensed; two pairs of sister chromatids

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16
Q

What is the chiasma?

A

point on sister chromatids where they remain intertwined during metaphase I

17
Q

What is the glue that holds non-sister chromatids together during meiosis I?

A

chiasmata

18
Q

What is a dyad?

A

half of a tetrad

19
Q

At the end of anaphase I, what has occurred?

A

there are a haploid number of dyads at each end pole

20
Q

What occurs during telophase I?

A

cytokinesis divides everything in two and the nuclear membrane reforms around the dyads