4. Pathogenesis of Bacterial Infection Flashcards
Which term refers to the processes that give rise to disease and result from both bacterial and host factors?
Pathogenesis
Which type of symbiosis is when a pathogen takes shelter in a host?
Commenalism
Typically, Mycobacterium tuberculosis and the influenza virus gain entry into humans via which route of transmission?
Inhalation
Which toxin is a major component of the outer membrane of Gram-negative bacteria?
Endotoxin
Which organism produces several exotoxins that are important in the pathogenesis of food poisoning?
Staphylococcus aureus
What superantigen is produced by staphylococcus aureus?
Toxic Shock Syndrome Toxin-1
Which term best describes the ability of a pathogen to enter a host, overcome its defences, multiply and spread?
Invasiveness
Which Staphylococcus aureus enzyme converts fibrinogen into a fibrin clot?
Coagulase
What is a pathogen?
A micro-organism that can cause disease
What is virulence?
Severity of a micro-organism’s ability to cause disease
What enzyme is produced by staph aureus?
What does it do?
Coagulase
converts fibrinogen to fibrin
What is the function of streptokinase?
Lysis of firbin clots
What parts of the bacterium aid in adherance?
Fimbriae, cell wall, capsule
What are invasins?
Proteins that can bind to receptors on host cells
What are the 3 ways bacteria can evade the immune system?
Motility
Inhibition or survival of phagocytosis
Production of substances that help invasion