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FIM > 21. b. Listeria > Flashcards

21. b. Listeria Flashcards

1
Q

What patient groups are at a high risk of acquiring a listeriosis infection?

A

Immunocompromised
Pregnant
Neonates
Those who work with animals

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2
Q

How does listeria appear under the microscope?

A

Gram + bacillus

Shows tumbling motility at 25C

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3
Q

Give some metabolic factors of listeria

A

Faculative anaerobic

Can grow from 2-37C

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4
Q

What type of haemolysis does listeria display?

A

Beta

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5
Q

How is listeria acquired?

A

Animal contact
Contaminated foods
Vertical from mother to foetus

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6
Q

How does listeria spread through the body?

A

Survive and multiply within macrophages

Spread from cell to cell without entering bloodstream

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7
Q

What immune cell is needed to kill listeria?

A

T cells

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8
Q

How does listeria present in most people?

A

Asymptomatic or mild flu or diarrhoea

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9
Q

How does an occupational exposure to listeria present?

A

Flu

Gastroenteritis

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10
Q

What diseases can listeria cause in immunosuppressed people?

A

Pneumonia

Meningoencephalitis

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11
Q

What is perinatal listeriosis?

A

‘Influenza-like illness’ in third trimester

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12
Q

What are the consequences of perinatal listeriosis?

A

Miscarriage and interuterine death
Premature labour and an infected infant
Neonatal listeriosis

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13
Q

When does early neonatal listeriosis present?

A

1st 2 days of life

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14
Q

Where is early neonatal listeriosis acquired?

A

Intrauterine

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15
Q

What diseases are caused by early neonatal listeriosis?

A

BSI +/- pneumonia and cardiopulmonary distress

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16
Q

What are possible consequences of early neonatal listeriosis?

A

Hepatosplenomegaly
Abscesses
CNS involvement
High mortality

17
Q

When does late neonatal listeriosis present?

A

> 5 days old

18
Q

Where is late neonatal listeriosis acquired?

A

Genital tract

19
Q

What diseases are caused by later neonatal listeriosis?

A

Meningitis/ meningoencephalitis

20
Q

What samples can be taken from the mother to diagnose listeriosis?

A

Blood
Urine
High vaginal swab
Placenta

21
Q

What samples can be taken from a neonate to diagnose neonatal listeriosis?

A

Blood
CSF
Meconium

22
Q

What treatment is given for listeriosis?

A

High dose ampicillin/amoxicillin and aminoglycoside

23
Q

What class of antibiotics is listeria resistant to?

A

Cephalosporins

FIM (44 decks)

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