20. c. Rubella Flashcards
What is the genus of rubella?
Togavirus
Is rubella a DNA or RNA virus?
RNA
How long is the incubation period for rubella?
12-23
How long is rubella infectious for?
7 days before to 7 days after rash
How is rubella acquired?
Droplet inhalation
Where does rubella replicate?
Respiratory tract
Lymph nodes
What is the prodrome of rubella?
Low grade fever
What are the clinical features of rubella?
Lymphadenopathy
Maculopapular rash
What nodes are most often involved in rubella?
Post-auricular
Post cervical
Suboccipital
How is the rubella rash differentiated from the measles rash?
Non-blanching
Fainter than measles
Doesn’t coalesce
What complications are associated with rubella?
Congenital rubella syndrome Arthralgia and arthritis Post infectious encephalitis Haemorrhage Conjunctivitis Orchitis
What defects are associated with congenital rubella syndrome?
Deafness Cataracts Heart defects Microcephaly and intellectual disability Bone alterations Liver and spleen damage
How can congenital rubella syndrome be prevented?
Antenatal screening
What samples can rubella PCR be done on?
Respiratory secretions
Oral fluid
Urine
Blood
What lab tests can be done to diagnose rubella?
PCR
serology
culture