20. b. Mumps Flashcards
Is mumps a DNA or RNA virus?
RNA
What is the genus of mumps?
Paramyxovirus
Where does mumps replicate?
Nasopharynx and regional lymph nodes
How long after exposure does viraemia occur?
12-25 days
How long is the incubation period for mumps?
12-25 days
What time of year does the mumps peak?
Later winter/spring
What time period is the mumps infectious for?
3 days before to 5 days after the onset of illness
How is the mumps acquired?
Droplet inhalation or deposition on eyes, nose or mouth
What allows mumps to adhere to respiratory tract cells?
Proteins in the glycoprotein envelope
Where does the mumps virus migrate to after attaching to respiratory tract epithelial cells?
BALT and draining lymph nodes
Replicate in T cells
What parts of the body does the mumps spread to?
Meninges
Salivary glands
Testicles
Ovaries
What is a prodrome?
Early symptoms
What prodromes are associated with the mumps?
Low-grade fever
Headache
Malaise and myalgia
What are the symptoms of mumps infection?
Parotitis which may be unilateral
Lower RTI in young children
Which group of people tend to be more severely affected by the mumps?
Adults