19. Immunisation Flashcards
What is an antigen?
Live or inactivated substance capable of producing an immune response
What is an antibody?
Immunoglobulin produced by B cells to help eliminate an antigen
What is an adjuvant?
Substance that increases the antibody response
Name 2 adjuvants
Aluminium phosphate
Aluminium hydroxide
What is immunisation?
Process of artificially inducing or providing immunity to an infectious disease
What indicates how successful a vaccine is?
Presence of antibodies
What is passive immunity?
Injection of antibodies
Immediate but short lived protection
Name 2 forms of passive immunity
Post Exposure Prophylaxis
Transplacental
What is active immunity?
Stimulates host production of immune response
May be live or non live
Name the forms of non-live vaccines
Whole inactivated
Protein based
Polysaccharide based
Recombinant
How is a whole inactivated vaccine created?
Pathogen is killed by heat or formalin
How many doses are needed for a whole inactivated vaccine?
3-5
What sort of response is generated by a whole inactivated vaccine?
Humoral
Name 2 whole inactive vaccines
Polio
Hep A
What vaccines are live and must not be given to immune compromised patients?
BCG
MMR
Varicella