18. a. Chlamydia Flashcards

1
Q

What gram staining is chlamydia?

A

negative

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2
Q

Why is chlamydia an obligate intracellular organism?

A

Needs host ATP to replicate

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3
Q

What is the elementary body?

A

Chlamydia outside of the host cell
Infectious but not metabolically active
Phagocytosed into the host cell

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4
Q

What is the reticulate body?

A

Intracellular form of chlamydia

Metabolically active but not infectious

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5
Q

How does C. Psittsaci get into the body?

A

Inhalation of bird droppings

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6
Q

What is the incubation period for C. Psittsaci?

A

1-3 weeks

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7
Q

What are the symptoms of C. Psittsaci?

A

Flu-like symptoms and pneumonia

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8
Q

What are the complications of C. Psittsaci?

A
Respiratory failure
Hepatitis
Endocarditis
Encephalitis
Life-threatening in pregnancy
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9
Q

What type of pneumonia is caused by C. Pneumoniae?

A

Atypical non-culturable

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10
Q

Who is at risk for C. pneumoniae?

A

Older adults

Close quarters

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11
Q

What is the incubation period for c. pneumoniae?

A

3-4 weeks

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12
Q

What diseases are caused by c. pneumoniae?

A
Pneumonia and pharyngitis
Meningoencephaltis
Guillain-Barre syndrome
Reactive arthritis
Myocarditis
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13
Q

What is the treatment for c.psittsaci and pneumoniae?

A

Tetracycline or macrolides

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14
Q

Why is penicillin not used to treat psittaci and pneumoniae?

A

There is no peptidoglycan in the cell wall

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15
Q

What lab tests can be used to diagnose psittaci and pneumoniae?

A

PCR
Serology
Cell culture

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16
Q

How is c.trachomatis spread?

17
Q

What disease is caused by the A-C serotypes of c. trachomatis?

18
Q

What disease is caused by the D-K serotypes of c. trachomatis?

A

Inclusion conjunctivitis
Neonatal pneumonia
STI

19
Q

What disease is caused by the L serotype of c. trachomatis?

A

Lymphogranuloma venereum

20
Q

How is trachoma treated?

A

Surgery to stop eyelashes scraping the cornea

Antibiotics

21
Q

How is inclusion conjunctivitis treated?

A

Azithromycin or doxycycline

22
Q

What diseases does the C. trachomatis STI cause in women?

A

Cervicitis
Urethritis
Pelvic inflammatory disease
Pregnancy complications

23
Q

What diseases does the C. trachomatis STI cause in men?

A

Urethritis
Epididymitis
Proctitis

24
Q

What antibiotics are used to treat C. trachomatis STI?

A

Macrolide or doxycycline

25
What is the presentation of lymphogranuloma venereum?
Genital ulcer Painful lymphadenopathy Proctocolitis if anal sex
26
What lab tests can be done in the case of lymphogranuloma venereum?
PCR | Serology
27
How is lymphogranuloma venereum treated?
Aspirate buboes | Doxycycline