18. a. Chlamydia Flashcards

1
Q

What gram staining is chlamydia?

A

negative

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2
Q

Why is chlamydia an obligate intracellular organism?

A

Needs host ATP to replicate

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3
Q

What is the elementary body?

A

Chlamydia outside of the host cell
Infectious but not metabolically active
Phagocytosed into the host cell

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4
Q

What is the reticulate body?

A

Intracellular form of chlamydia

Metabolically active but not infectious

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5
Q

How does C. Psittsaci get into the body?

A

Inhalation of bird droppings

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6
Q

What is the incubation period for C. Psittsaci?

A

1-3 weeks

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7
Q

What are the symptoms of C. Psittsaci?

A

Flu-like symptoms and pneumonia

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8
Q

What are the complications of C. Psittsaci?

A
Respiratory failure
Hepatitis
Endocarditis
Encephalitis
Life-threatening in pregnancy
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9
Q

What type of pneumonia is caused by C. Pneumoniae?

A

Atypical non-culturable

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10
Q

Who is at risk for C. pneumoniae?

A

Older adults

Close quarters

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11
Q

What is the incubation period for c. pneumoniae?

A

3-4 weeks

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12
Q

What diseases are caused by c. pneumoniae?

A
Pneumonia and pharyngitis
Meningoencephaltis
Guillain-Barre syndrome
Reactive arthritis
Myocarditis
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13
Q

What is the treatment for c.psittsaci and pneumoniae?

A

Tetracycline or macrolides

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14
Q

Why is penicillin not used to treat psittaci and pneumoniae?

A

There is no peptidoglycan in the cell wall

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15
Q

What lab tests can be used to diagnose psittaci and pneumoniae?

A

PCR
Serology
Cell culture

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16
Q

How is c.trachomatis spread?

A

Contact

17
Q

What disease is caused by the A-C serotypes of c. trachomatis?

A

Trachoma

18
Q

What disease is caused by the D-K serotypes of c. trachomatis?

A

Inclusion conjunctivitis
Neonatal pneumonia
STI

19
Q

What disease is caused by the L serotype of c. trachomatis?

A

Lymphogranuloma venereum

20
Q

How is trachoma treated?

A

Surgery to stop eyelashes scraping the cornea

Antibiotics

21
Q

How is inclusion conjunctivitis treated?

A

Azithromycin or doxycycline

22
Q

What diseases does the C. trachomatis STI cause in women?

A

Cervicitis
Urethritis
Pelvic inflammatory disease
Pregnancy complications

23
Q

What diseases does the C. trachomatis STI cause in men?

A

Urethritis
Epididymitis
Proctitis

24
Q

What antibiotics are used to treat C. trachomatis STI?

A

Macrolide or doxycycline

25
Q

What is the presentation of lymphogranuloma venereum?

A

Genital ulcer
Painful lymphadenopathy
Proctocolitis if anal sex

26
Q

What lab tests can be done in the case of lymphogranuloma venereum?

A

PCR

Serology

27
Q

How is lymphogranuloma venereum treated?

A

Aspirate buboes

Doxycycline