11/12

Question 1

What is given in syringe driver to prevent local reaction when someone has had previous reaction?

Answer 1

Low dose dexamethasone

Question 2

What are the two purposes of prescribing haloperidol in palliative pts?

Answer 2

Nausea
Intense dreamings/hallucinations

Question 3

What are the symptoms of lithium toxicity?

How is it managed?

Answer 3

Coarse tremor
Confusion
Jerking leg movements
Reduced GCS

Hydration and supportive management

Question 4

What antibodies are tested for in Graves?

Answer 4

TRAb - autoantibodies against the thyroid stimulating hormone receptor

Question 5

PBC and PSC are diseases of middle age.
Describe the differences between the two

Who gets them?

Which one is linked with UC?

How do they both present?

What is the AB assoc. with PBC
What will bloods look like?

Which one responds to ursodeoxycholic acid?

Answer 5

PSC - repeated scarring and stricture formation in the bile ducts both intra and extrahepatically (hence the “beads on the string” appearance on USS)

PBC - AUTOIMMUNE condition which destroys the bile ducts in the liver

PBC = women (B = Boobs)
PSC = men and UC

FATIGUE
jaundice
puritus
~ fever and RUQ

anti-microchondrial antibodies - PBC
Raised ALP in both

PBC = ursodeoxycholic acid helps to reduce the progression

Question 6

The clinical presentation difference between fat embolism and pulmonary embolism?

Answer 6

Fat embolism often after trauma and presents with neurological symtpoms
- confusion
- altered levels of conciousness
- focal deficits

Can also get a petechial rash 24hrs after syndrome appears but this is rare

UNLIKE PE