XII: Chapter 5- Principles of inheritance and variations Flashcards
When did Mendel conduct his experiment on peas?
1856 to 1863 ( 7 years)
How many true breeding pea plant varieties did Mendel select?
14
What are the units of inheritance?
Genes
What does the I gene in ABO blood groups control?
The kind of sugar on the surface of RBC
Morgan crossed yellow bodied, white eyed male fruit flies with brown bodied, red eyed female fruit flies to get F1 generation. True/false?
False.
Morgan crossed yellow bodied, white eyed female fruit flies with brown bodied, red eyed male fruit flies to get F1 generation.
What percent of the offspring obtained in F2 generation were recombinants when yellow bodied, white eyed female fruit flies with brown bodied, red eyed male fruit flies were crossed?
1.3%
What percent of the offsprings obtained in F2 generation were recombinants when white and miniature wings were taken as characters in fruit flies?
37.2%
Phenylketonuria is caused by the mutation of which gene?
It is caused by mutation in gene that codes for enzyme phenyl alanine hydroxylase.
Who discovered X chromosome?
Henking
How many chromosomes does a female honeybee have?
32
What type of disorder is cystic fibrosis-Mendelian disorder or chromosomal disorder?
Mendelian disorder
Is myotonic dystrophy dominant or recessive? Is it sex linked?
Autosomal dominant
In colour blindness, defect is caused in
red or green cones of the eye
Why is sickle cell anaemia caused?
Substitution of glutamic acid by valine at the six position of the bets globulin chain of haemoglobin
Is phenylketonuria sex linked?
No
What happens due to the absence of phenyl alanine hydroxylase in phenyl ketonuria patient?
Phenylalanine is not converted into tyrosine, so phenylalanine is accumulated and converted to phenylpyruvic acid.
What causes thalassemia?
Mutation or deletion in gene which causes reduced rate of formation of α or β globin chains of haemoglobin.
α- Thalassemia is controlled by which genes?
Two closely linked genes HBA1 and HBA2 on chromosome 16 of each parent
α- Thalassemia can occur only because of mutation in one gene. True/false?
α- Thalassemia can occur because of mutation or deletion in one or more of the four genes (the genes being two closely linked genes HBA1 and HBA2 on chromosome 16 of each parent).
β- Thalassemia is controlled by which genes?
Single gene HBB on chromosome 11 of each parent
Down’s syndrome is caused due to
Trisomy of chromosome 21
Who coined the term genetics?
Bateson
What is the chemical basis of heredity?
DNA
What is the physical basis of heredity?
Gene
