XII: Chapter 12- Biotechnology and its application Flashcards
Give examples of lepidopterans.
Tobacco budworm, armyworm
Proteins coded by which genes control cotton bollworms?
Cry1Ac and Cry2Ab
Proteins coded by which gene control corn borers?
Cry1Ab
How were nematode specific genes introduced into the host plant?
Using agrobacterium vectors
How many therapeutics have been approved for human use worldwide and in India?
30 worldwide and 12 in India
When was genetically engineered insulin first produced?
1983
When was the first clinical gene therapy given?
1990
ADA deficiency stands for
Adenosine deaminase deficiency
As a first step towards gene therapy which cells of the ADA deficiency patient were cultured?
Lymphocytes
How was ADA cDNA introduced into cultured lymphocytes for gene therapy of ADA deficiency?
Using retroviral vector
No transgenic model exists for cystic fibrosis. True/false?
False. Transgenic models exist for cystic fibrosis.
No transgenic model exists for Alzheimer’s. True/false?
False. Transgenic models exist for Alzeihmer’s.
When was the first transgenic cow made?
1997
How many gram of protein was present per litre in the milk produced by Rosie the transgenic cow?
2.4g
GEAC stands for
Genetic engineering approval committee
In which year did an American company get patent rights on Basmati rice through the US Patent and trademark office?
1997
How many amino acids does insulin have in both of its chains?
A- chain : 21 amino acids
B-chain : 30 amino acids
What are second generation vaccines?
rDNA vaccines
What are third generation vaccines?
DNA vaccines
What is the use of interferon alpha therapeutic?
Treatment of cancer
What is the use of tissue plasminogen activator therapeutic?
Myocardial infarction
What is the use of the therapeutic DNAse?
Cystic fibrosis
What is the use of the therapeutic OKT-3?
immunosuppressive agent to prevent acute rejection in case of organ transplant
What is the use of the therapeutic GCSF?
Cancer treatment
