XI: Chapter 22- Chemical control and coordination Flashcards
Who is known as the father of endocrinology?
Thomas addison
Epinephrin is a derivative of
Tyrosine (amino acid)
Melatonin is a derivative of
Tryptophan
Thyroxine is a derivative of
Tyrosine
Which hormones are short polypeptide hormone?
Oxytocin and ADH
Which hormones are long polypeptide hormones?
Insulin and glucagon
What type of hormone are FSH and LH
Glycoproteins
Thyroid stimulating hormone is a
Protein
What type of hormone is follicle stimulating hormone?
Protein
Adrenal cortex homones are which type of hormones?
Steroids
Which germ layer did pitutary gland originate from?
Ectodermal
Which germ layer does adrenal medulla arise from?
Ectodermal
WHich germ layer do ovary and testis arise from?
Mesoderm
Which germ layer does adrenal cortex arise from?
Mesoderm
Which germ layer does thyroid gland arise from?
Endoderm
Which germ layer does parathyroid gland arise from?
Endoderm
Which hormones are rapidly acting?
Biogenic amines, protein hormones
The effects of which hormones are short lived?
Protein hormones, biogenic amines
Which hormones are slow acting but have long lasting effects?
Steroids, iodothyronins
Adenohypophysis consists of which lobes?
Pars distalis and pars intermidia
Neurohypophysis consists of which lobes?
Pars nervosa
Name the hormones secreted by pars distalis.
Growth hormone TSH Adrenocoricotrophic hormone Prolactin Follicle stimulating hormone LH
Name the hormones released by Pars intermedia
Melanocyte stimulating hormone
Name the hormones secreted by Pars nervosa
Oxytocin
Vasopressin
Anterior pitutary is formed by
Adenohypophysis
What kind of control does hypothalamus have over anterior pitutary?
Indirect control
What kind of control does hypothalamus have over posterior pitutary?
Direct nerual regulation
Hormones in anterior pitutary are stored in
Herring’s bodies
Melatonin is secreted by which gland?
Pineal gland
What effect does melatonin have on puberty?
Delays puberty
Which hormone is antagonistic to melanin?
Melatonin
What are the calcium deposits over the pineal gland called which appear at time of puberty?
Brain sand
Which is the largest endocrine gland?
Thymus
How many lobes does the thyroid gland have?
2
Which molecule is found in the colloid in thyroid follicles?
Thyroglobulin
Which tissue is present beneath the fibrous capsule of thyroid gland?
Loose areolar connective tissue (stroma)
T4 and T3 hormones are secreted by which cells?
Follicular cels
Thyrocalcitonin is secreted by which cell?
Parafollicular cells
Which is the only endocrine gland which stores its hormone in inactive state?
Thyroid gland
Which hormone is more potent- triiodothyronine or tetraiodothyronine?
triiodothyronine
How do T3 and T4 affect the number of mitochondria and ATP production?
the number of mitochondria and ATP production increase
How do T3 and T4 affect the heart rate and cardiac output?
The heart rate and cardiac output increase
Myxoedema is caused due to
Hypothyroidism in adulthood
Which is an autoimmune hypothyroidism disease?
Hashimoto’s thyroiditis
Exophthalmic goitre is also called
Grave’s disease
Grave’s disease is caused due to
Hyperthyroidism
What effect does thyrocalcitonin have on blood calcium levels?
Blood calcium ion levels decrease
How many parathyroid glands are present in body?
4
Which are the main hormone producing cells on parathyroid gland?
Chief cells
How does parathyroid hormone affect blood calcium levels?
Increases blood calcium levels
Hyposecretion of thyrocalcitonin causes
Tetany
How many islets of langerhans are present in pancreas?
1-2 million
Which cells of pancreas release glucagon?
Alpha cells
WHich cells of pancreas release insulin?
beta cells
Which cells of pancreas release somatostatin?
Delta cells
What is the function of somatostatin secreted by delta cells of the pancreas?
Inhibits the secretions of alpha and beta cells of pancreas
What is the role of glucagon?
Increase blood sugar level, gluconeogenesis, glycogenolysis
What is the target organ of glucagon?
Liver and adipose tissue
What is the role of insluin?
Decreases blood glucose level
What happens in non insulin dependent diabetes mellitus?
Target receptors become insensitive to insulin
What is the location of adrenal gland?
Anterior surface of kidney
How many zones does the adrenal cortex have?
Zona glomerulosa
Zona fasciculata
Zona reticularis
Mineralocorticoids are secreted by
Zona glomerulosa of adrenal cortex
Glucocorticoids are secreted by
Zona fasciculata of adrenal cortex
Sex corticoids are secreted by
Zona reticularis of adrenal cortex
Which hormone is secreted by zona glomerulosa of adrenal cortex?
ALdosterone
Which hormone is secreted by zona fasciculata of adrenal cortex?
Cortisol
Which hormone is secreted by Zona reticularis of adrenal cortex?
Gonadotrophins
What is the function of cortisol?
Hyperglycemic
How does cortisol act as an immunosuppressant agent?
By decreaseing lymphocyte formation in lymphoid tissue
Hypersecretion of aldosterone causes
Conn’s disease or aldosteronism
What happens to blood pressure in aldosteronism?
Blood pressure increases
Hypersecretion of cortisol leads to which disease?
Cushing’s syndrome
What happens in hypersecretion of sex corticoids?
Females-adrenal virilism
Males- gynacomastia
What is Addison’s disease?
Hyposecretion of mineralocorticoids and glucocorticoids
Which hormones are released by adrenal medulla?
Adrenalin, noredrenalin
Which hormones are known as love hormone?
Estrogen and prolactin
Which hormone is responsible for metamorphosis in frog?
Thyroid hormone
What are the neurosecretory cells of hypothalamus which secrete hormones called?
Nuclei
Hypothalmic hormones reach pitutary gland through
Portal circulatory system
How are the two lobes of thyroid gland connected?
Through thin connective tissue, isthmus
What are the symptoms of Addison’s disease?
Fatigue and acute weakness
Which hormones are commonly known as catacholamines?
Adrenaline, norepinephrine
Which hormone of adrenal gland has anti inflammatory response?
Cortisol
Which hormone is associated with milk secretion and formation?
Prolactin