Wernicke's Encephalopathy Flashcards

1
Q

What is Wernicke’s encephalopathy?

A

A neuropsychiatric disorder caused by thiamine deficiency, commonest in alcoholics

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2
Q

How does WE present?

A
  • Nystagmus
  • Opthalmoplegia: lateral rectus palsy, gaze palsy
  • Gait ataxia
  • Encephalopathy: confusion, disorientation, inattentiveness
  • Peripheral neuropathy
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3
Q

How is WE managed?

A
  • Urgent replacement of thiamine
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4
Q

What is the complication of WE?

A
  • Korsakoff syndrome: antero/retrograde amnesia as well as confabulation
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