Essential Tremor Flashcards
1
Q
What is an essential tremor?
A
The most common neurological movement disorder in adults
2
Q
What are risk factors for essential tremor?
A
- Older age
- FH (AD inheritance)
- Toxins e.g lead, mercury
3
Q
What is the pathophysiology of ET?
A
- Not fully established by linked to dysfunction of the GABA circuit
4
Q
How does ET present?
A
- Tremor worsened by intentional movements but not present at rest
- Worsens when arms outstretched
- Bilateral
- 6-12 Hz in frequency
- Relieved by alcohol
- Worsened by anxiety, excitement
5
Q
How is ET diagnosed?
A
- Clinical diagnosis
- Bloods: U+E, TFTs to exclude other causes
6
Q
How is ET managed?
A
- Propranolol/Primidone first line
- Other medications include gabapentin, topiramate
- Referral for patients refractory to medical treatment
