Viruses Flashcards
What is the viral Genome encapsulated in
Capsomere
Virus size
From 15nm to 0.5 micro metres
Viral latency
Virus lies dormant within a cell
Viral pathogenesis
Process by which a viral infections cause disease
Requirements for infection
Enough virus, cells accessible, susceptible and permissive, local anti-viral defence absent or overcome
What is the most common route of entry for a virus
Respiratory tract – by aerosolise droplets from coughs/sneeze/saliva
Alimentary tract
Eating/drinking- an extremely hostile environment, virus must be evolved to with stand it
The Urogenital tract is protected by
Mucus and a low pH
The eye and entry routes for bacteria
Through the Sclera and conjunctiva- Infection occurs after injury/ophthalmology procedures
Skin outer layer the epidermis doesn’t support
Infection
Localised viruses are called
Disseminated
When many organs are affected by viruses it is called
Systemic
What is haematogenous spread
Where the virus enters the blood e.g. measles
What is viremia 
Presence of virus in the blood e.g. influenza, polio
What is neural spread
Viral entry into local nerve endings they invade the central nervous system e.g. polio virus, rabies