Skin Principles Flashcards
What are the three layers of the skin
Epidermis, Dermis, subcutis
The epidermis has
Keratinising stratified epithelium, natural openings for hair follicles
The four layers of the epidermis
Horn cell layer, granular cell layer, prickle cell layer, basal cell layer
What are keratinocytes held together by and anchored by
They are held together by desmosomes and anchored to the basement membrane by hemidesmosomes
Where are Melanocytes located
In the basal layer
Where did melanocytes originate from
The dendritic cells originated from the neural crest
What do you melanocytes do
Produce melanin And protect against UV, they also help determine skin colour
What does the basement membrane do
Joins epidermis to dermis
What is the basement membrane made out of
A type of IV collagen
What is special about the basement membrane
It Is resistant to shearing forces
What does the basement membrane provide
Structure and controls the interaction of the epithelial mesenchymal
What is the dermis made of
Collagen and elastic fibres, they also have fibroblasts and histocytes
What does the dermis do
Supports the epidermis
Fibroblasts
They are spindle shape cells in the extracellular matrix and collagen, they are used in wound healings
Histocytes/ Macrophages
Eat debris to get rid of stuff, bean shaped nuclei and they are fully differentiated
