Vancomycin Flashcards

1
Q

Generic Name for Vancocin

A

Vancomycin

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2
Q

Trade Name for Vancomycin

A

Vancocin

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3
Q

Classification for Vancomycin

A

Antibiotic

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4
Q

MOA (pharmacodynamics) for Vancomycin

A

Binds to bacterial cell membranes, inhibits wall synthesis; bactericidal

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5
Q

Indications for Vancomycin Admin

A

Treatment of susceptible infections due to gram-positive aerobic bacteria like staphylococcus. It treats complicated skin infections, bloodstream infections, endocarditis, bone/joint infections and meningitis. Often used to treat MRSA.

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6
Q

Dosages for Vancomycin Admin

A

Adult: 25-30mg/kg IV/IO ideal body weight.

  • doses 1g or less; Infuse over 60 minutes
  • doses 1g to 1.5g; Infuse over 90 minutes
  • doses over 1.5g; Infuse over 120 minutes

Pediatric: 15mg/kg to a max of 1000mg IV/IO, infuse over 60 minutes

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7
Q

Contraindications for Vancomycin Admin

A
  1. Hypersensitivity
  2. Hemolytic anemia
  3. c.difficile associated diseases
  4. Do not administer with calcium containing IV solutions such as ringers lactate.
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8
Q

Precautions in using Vancomycin

A
  • Rapid injection may cause Red Man syndrome (anaphylactoid reaction causing hives, swelling, rash to face, hands, neck and upper torso).
  • Slowing the infusion rate and increasing dilution volume may prevent or minimize this reaction
  • Administering an antihistamine prior to the infusion may reduce symptoms
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9
Q

Notable Notes to Note regarding Vancomycin

A
  • Abdominal cramping, severe watery diarrhea, and fever may result from an altered bacterial balance.
  • Use caution in patients with impaired renal function and patients with previous hearing problems.
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