Diltiazem

Question 1

Generic name for Cardizem?

Answer 1

Diltiazem

Question 2

Trade name for diltiazem?

Answer 2

Cardizem

Question 3

Classification - diltiazem

Answer 3

Class IV-Calcium Channel Blocker

Question 4

What is diltiazem supplied in?

Answer 4

5 mg/ml (10 ml vial), 25 mg preload

Question 5

Pharmacodynamics - diltiazem

Answer 5

❑ Antiarrhythmic:

• impedes the slow inward influx of calcium at the AV node thus decreasing conduction velocity and increasing the refractory period
• decreases A-fib or Aflutter
• decreases ventricular rate.

Question 6

Indications (2) - diltiazem

Answer 6

❑ Tachy A-Fib or A-Flutter

❑ rentry SVT (with narrow QRS complex and adequate blood pressure) refractory to adenosine

Question 7

Dose: first, second and maintenance

*I think this is Diltiazem?? Need to update card to be sure.

Answer 7

1st Dose: 0.25 mg/kg SIVP;

2nd Dose: 0.35 mg/kg SIVP;
-15 minutes after 1st dose

Maintenance Infusion: For acute rate control of A-Fib or atrial flutter maintenance is initiated at a rate of 5 to 15 mg/hr titrated to the patient’s heart rate.
Mix: 50mg in 500ml NS (concentration 0.1mg/ml)

Question 8

Contraindications (8) - diltiazem

Answer 8

❑ Hypersensitivity
❑ Wide-QRS tachycardia of uncertain origin
❑ Poison-or drug-induced tachycardia.
❑ Sick Sinus Syndrome
❑ WPW
❑ Bradycardia; second or third degree AV block
❑ LV dysfunction; Heart Failure
❑ Hypotension

Question 9

Precautions - diltiazem

Answer 9

❑ heart failure
❑impaired hepatic or renal function
❑ taking Beta-Blockers or Calcium Channel Blockers – use in extreme caution
❑ Not recommended for pediatrics