Dimenhydrinate

Question 1

Generic Name For Gravol

Answer 1

Generic Name For Gravol is Dimenhydrinate

Question 2

Trade Name For Dimenhydrinate

Answer 2

Trade Name for Dimenhydrinate is Gravol

Question 3

Dimenhydrinate Classification

Answer 3

Dimenhydrinate Classification is; Antiemetic, antivertigo and antihistamine

Question 4

MOA (pharmacodynamics) for Dimenhydrinate

Answer 4

Dimenhydrinate is a histamine H1 and ACh receptor antagonist that acts as an antiemetic and antivertigo medication. Centrally blocking these receptors depresses the sensitivity of the labyrinth apparatus that normally relays stimuli to the CTZ and vomiting center of the brain.

Question 5

Indications for Dimenhydrinate Admin

Answer 5

Dimenhydrinate is indicated for treatment of nausea, vomiting, and dizziness associated with motion sickness, vertigo, and narcotic administration.

Question 6

Dosage for Dimenhydrinate

Answer 6

Dose for Dimenhydrinate:

Adults: 25-50 mg SIVP; diluted with NS to 10 ML; or 50-100 mg IM/PO, repeat every 4 hours

Peds: 1 mg/kg slow IM/IV/IO push. Max 25 mg q 4 hours

Question 7

Contraindications for Dimenhydrinate (3)

Answer 7

1. Hypersensitivity
2. Any condition that may be worsened by anti-cholinergic effects
3. Patients who have ingested a large amounts of depressants, including ET0H

Question 8

Precautions when administering Dimenhydrinate

Answer 8

• Ensure the use of a z track method when giving IM to avoid subcutaneous irritation.
• Use cautiously in patients with seizures and acute narrow angle glaucoma.

Question 9

Notable notes for Dimenhydrinate

Answer 9

Dimenhydrinate may cause children under the age of 6 to experience paradoxical hyper-excitability.
IV dose for children has not yet been established (yet there’s a peds dose above?).
Administer IM injections in the lateral quad (vastus lateralis)