Prednisone

Question 1

What is the trade name of prednisone?

Answer 1

Novo-Prednisone

Apo-Prednisone

Question 2

What is the classification of prednisone?

Answer 2

glucocorticoid

mineralcorticoid

Question 3

How is prednisone supplied?

Answer 3

5mg tablets

5mg/ml syrup

20mg/ml suspension for injection

Question 4

What is the MOA (pharmacodynamics) of prednisone?

Answer 4

• Inhibits accumulation of inflammatory cells at inflammation sites, phagocytosis, lysosomal enzyme release/synthesis, release of mediators of inflammation.
• Prevents/suppresses cell-mediated immune reactions.
• Decrease/prevents tissue response to the inflammatory process.
• Increase the amount of beta 2 receptors available

Question 5

List the indications of prednisone

Answer 5

• Anaphylaxis

- Bronchospasm – Asthma; COPD

Question 6

What is the dosage for prednisone?

Answer 6

50 mg PO

Question 7

List the contraindications for prednisone.

Answer 7

• Hypersensitivity
• Patients already on prednisone
• Altered LOC/unable to tolerate oral medication
• System fungal infections

Question 8

What are some of the precautions in the use of

prednisone.

Answer 8

• Recent MI, Heart Failure
• GI ulcer
• Renal disease
• HTN
• Osteoporosis
• DM
• Hypothyroidism
• Cirrhosis
• Seizures
• Myasthenia gravis
• TB