URINALYSIS Flashcards
the amount of filtered plasma
170,000 mL
average daily urine output
1200 - 1500 mL (range of 600 – 2000 mL is considered normal)
The MORE FLUID will intake, urine volume will ____
increase
The LESSER FLUID will intake, urine volume will _____
decrease
the concentration of urine is directly proportional to the ______
specific gravity
“Concentrated Urine”, because urine is “concentrated” the color also affected, it becomes ______.
DARKER
the less concentrated the urine is, the lesser is the _____ of the urine.
color (lighter)
testing of urine with procedures commonly performed in expenditure, reliable, accurate, safe and cost-effective manner.
urinalysis
purpose of urinalysis
- to detect renal disease
- for metabolic screening procedure
- test from asymptomatic beginnings of conditions such as Diabetes Mellitus, Diabetes Insipidus and Liver Diseases
pathways in urine
- glomerulus
- bowman’s capsule
- proximal convoluted
- loop of henle
- distal convoluted tubules
- collecting tubules
- ureter
- urinary bladder
- urethra
renal tubular epithelial cells in nephrotic sundrome, absorb and become engaged with fat known as
OVAL FAT BODIES
indicates lipid droplets contained in the cell
maltese cross
abnormal increase (>2500 ml per 24hrs)
polyuria
polyuria is associated with
diabetes mellitus and diabetes insipidus; or the use of diuretics, caffeine or alcohol which suppress the excretion of ADH.
decrease urine volume (<500 ml per 24hrs) and seen in a state of dehydration
oligouria
oliguria causes
excessive water loss, vomiting, diarrhea, perspiration or severe burns
oliguria is associated with
acute nephritis and shock
- complete suppression of urine formation
- may result from any serious damage to the kidneys or from a decrease in the flow of blood to the kidney
- <100mL/24hrs for 3 consecutive days
anuria
increased urine volume at night
nocturia
involuntary voiding of urine at night
enuresis
urine is composed mainly of __% of water and ___% of solids
95-97% of water and 3-5% of solids
urine is composed of ____ organic and ____ inorganic substances
35g organic and 25g inorganic substances
- the major organic constituent
- metabolic waste product produced by the liver from the breakdown of protein and amino acids
urea
volume of urea composition
25g/L
major inorganic constituent
chloride
volume of chloride composition
9g/L
Na, K in urine
- lesser amount present
- Na is 4g/L primary from salt, varies by intake
- K is 2g/liter, combined with Cl and other salts
product of creatine metabolism by muscles
creatinine
volume of creatinine in urine
1.5g/L
combines with sodium to buffer the blood
phosphate
volume of phosphate in urine
2g/L
product of nucleic acid breakdown in food and cell
uric acid
uric acid volume in urine
0.6g/L
regulates blood and tissue fluid acidity
ammonium
ammonium volume in urine
0.6g/L
combines with chloride, sulfate and phosphate
calcium
calcium volume in urine
0.2g/L
urine may also contain
- hormones, vitamins, medications and formed elements
formed elements in urine
- cells
- cast
- crystals
- mucus
- bacteria
To determine whether a particular fluid is urine
UREA-CREATININETEST
The specimen can be tested for its ____ and _____ content. Because both these substances are present in much higher concentrations in urine than in other body fluids, a high urea and creatinine content can identify a fluid as urine.
UREA ; CREATININE
Urine volume depends on the amount of _____ that the kidneys excrete
water
Major Body Constituent; therefore, the amount
excreted is usually determined by the body’s state of hydration.
water
FACTORS THAT INFLUENCE URINE VOLUME:
1) Fluid intake
2) Fluid loss from non-renal sources
3) Variations in the secretion of antidiuretic hormone (ADH)
4) Need to excrete increased amounts of dissolved solids, such as glucose or salts.
the concentration of urine is directly proportional to the ______
specific gravity
FACTORS INFLUENCING URINE CONCENTRATION:
1) Dietary intake
2) Physical activity
3) Body metabolism
4) Endocrine functions
5) Body position
urine normal color
straw to amber yellow
yellow pigment
urochrome
pink pigment - ppt of amorphous urates
uroerythrin
oxidation product of urobilinogen w/c is orange-brown color
urobilin
color is due to increase urobilinogen or porphyrin
reddish amber
reddish amber colored urine is associated with
1) Congenital porphyra
2) Lead and barbital poisoning
3) Pernicious anemia
4) Haemolytic jaundice
color is due to bile pigment
Brownish yellow or Green to yellow foam
Brownish yellow or Green to yellow foam colored urine is associated with
1) Severe hepatocellular damage
2) Obstruction of lesion of bile
flow
urine color due to Due to the presence of blood (hematuria) or blood pigment (hemoglobinuria)
Smoky red to brown
Smoky red to brown urine is associated with
1) Acute nephritis
2) Infants in kidneys
3) Bleeding lesions in urogenital
tracts
urine color due to increase/high urobilinogen
yellow to amber
yellow to amber colored urine is associated with
1) Blood destruction 2) Liver disease
milky urine appearance is due to
Due to increase/high chylomicron, fats, pus, epithelial cells, urease, phosphates, & bacteria
Due to melanin pigments (melanoma)
Brownish black to brown black
urine color due to hemogenphysic acid or alkapton
black
black colored urine is associated with
alkaptonuria
urine color due to biliverdin
Greenish foam
normal urine odor
aromatic due to “urinod” or “volatile organic acids”
ammoniacal odor is caused by
bacteria (proteus) convert urea to ammonia
fruity odor is caused by
ketones (indicates diabetes, ketonuria)
putrid odor indicates
presence of pus (necrotic lesion of the GUT, carcinoma, cystitis, pyelonephritis)
maple syrup-like odor is due to
increased valine, leucine, isoleucine = maple syrup disease
pungent odor is due to
onion, garlic, asparagus
mousy odor is due to
pku
rancid odor is due to
tyrosinemia
sweaty feet odor is due to
isovaleric academia
cabbage odor is due to
methionine malabsorption
bleach odor is due to
contamination
normal transparency
clear and nubecula
clear urine indicates
fresh specimen
faint cloud in urine forms after standing it for some time due to mucus, leukocytes, or epithelial cells
nubecula
Few particulates, print easily seen through urine
hazy
Many particulates, print blurred through urine.
cloudy
Print cannot be seen through urine
turbid
May precipitate or be clotted
milky
normal urine volume is adult
800-1600 ml/24hrs
normal urine volume in children (6-12 yrs old)
500-1500 ml/24hrs
normal urine in children (1-6 yrrs old)
300-1000 ml/24hours
the ratio of the weight of a substance to the weight of an equal volume of a reference substance
sg
urine sg is high, usually above 1.010
hypersthenuric
urine sg is normal, fixed at about 1.010
isosthenuric
urine sg is low, usually less than 1.007
hyposthenuric
low sg =
chronic nephritis, diabetes insipidus
high sg =
diabetes mellitus, acute nephritis, fever