infection control Flashcards
development of an infection and disease
pathogenesis
involves the growth and multiplication of microorganisms that cause damage to the host
infection
Bodily invasion of pathogenic microorganisms that reproduce, multiply, and then
cause diseases through local cellular injury, toxin secretion, or antigen-antibody
reaction in the host.
infection
an infection caused by a microorganism from the microbiota of the host.
autogenous infection
an infection that occurs as the result of some medical
treatment or procedure.
iatrogenic infection
an infection that affects immunocompromised hosts but not the individuals with a normal immune system.
opportunistic infection
also known as the hospital-acquired infection and type of infection that is acquired at a healthcare facility
nosocomial infection
the cornerstone of modern infection control programs
hand washing
4 common types of nosocomial infections
urinary tract infection
lung infection
surgical site infection
blood stream infection
Predisposing factors to nosocomial infections
a. Wide variety of microbes in the hospital environment
b. Weakened or immune-compromised patients
the chain of transmission
i. From health workers to patients
ii. From patient to patients
iii. Use of fomites
iv. Airborne transmission
v. Vector-borne transmission
signs and symptoms are confined in one area such as infected wounds, boils and abscesses
local infection
starts as a local infection before spreading to the other parts of the body such as tooth infection, tonsillitis, appendicitis, and wound infections caused
by Clostridium tetani.
focal infection
microbes spread throughout the body through the blood or lymph.
systemic infection (generalized infection)
– presence of bacteria in the blood.
- organisms invade the bloodstream without active multiplication
- Highest concentration of bacteria in the blood occurs before the fever spikes.
bacteremia
active multiplication of the invading bacteria in the blood.
septicemia
condition wherein pus-producing organisms repeatedly invade the bloodstream and become localized at different parts of the body.
pyemia
an initial infection that causes the illness such as colds
primary infection
an infection caused by opportunistic pathogens after the primary infection has weakened the host’s immune system such as pneumonia and bronchitis that may develop from a common cold.
secondary infection
clinically silent inside the body and causes no
noticeable illnesses in the host. Then severe and acute infection manifests such as asymptomatic type polio infection
Latent infection (Silent phase)
an infection caused by two or more organisms such as wound infection
mixed infection
type of infection that develops and progresses slowly
such as whooping cough
Acute infection
an infection which develops slowly with milder but
longer-lasting symptoms such as tuberculosis
chronic infection
2 routes of infection
direct and indirect
- Congenital contact – Strept.agalactiae, Neisseria gonorrhoeae and Treponema
pallidum - Sexual contact – N.gonnorrhoeae and T.pallidum
- Infectious respiratory secretions or droplets – Strept.pyogenes and N.meningitidis
- Hand-to-hand transmission – Rhinovirus
direct transmission
transmission through fomites, water and arthropod vectors
indirect transmission
A specific illness or disorder that is characterized by a recognizable signs and symptoms which are attributable to heredity, infection, and environment.
disease
It results when the infection produces notable changes in the human physiology, specifically those that cause damage to the body’s organ system
disease
infectious disease classification
communicable or contagious and non-communicable disease
spreads from one host to another, either
directly or indirectly. such as the tuberculosis, herpes, flu, and chickenpox
communicable or contagious disease
does not spread from one host to another and is caused by external microbes or by opportunistic pathogens living in the body. Examples are tetanus and botulism
non-communicable disease
occurence of disease classification
sporadic
endemic
epidemic
pandemic
occurs occasionally
sporadic disease
constantly present in a particular location or population.
endemic disease
disease that affects a large number of people in a population within a short period of time.
epidemic disease
disease that affects populations across large regions around the world.
pandemic disease
infectious disease effects
signs
symptoms
syndrome
these are objective changes that can be measured.
- Examples are fever, redness, swelling, and paralysis
signs
are subjective indications of the disease in a person
- Examples are pain and malaise
symptoms
is a group of signs and symptoms that are associated with a disease.
- Example is AIDS
syndrome
phases of infectious diseases
incubation period
prodromal period
clinical or illness period
decline period
convalescence or period of recovery
the time between the exposure to a pathogenic organism and the onset of symptoms.
incubation period