UNIT 9 Insulin CHAPTER 50 Flashcards
What is Diabetes? What are the signs and symptoms
Chronic disease of deficient glucose
metabolism
Insufficient insulin secretion from beta
cells
Impaired insulin use
Major symptoms: polyuria, polydipsia,
polyphagia
How many types of Diabetes are there, and what does it represent?
Types
Type 1
Insulin-dependent DM
Type 2
Insulin resistant
Secondary
Due to medications (glucocorticoids, thiazide
diuretics, epinephrine)
Gestational
Due to hormonal changes
What is the action of insulin?
Action
Promote use of glucose by body cells, store
glucose as glycogen in muscles
Use
Reduce blood glucose in diabetes
INSULIN
What are the side effects of of Insulin
Hypoglycemia
Headache, dizziness, confusion, slurred speech,
hunger, weakness
Nervousness, anxiety, agitation
Tremors, sweating
Flushing, lethargy
Redness, irritation or swelling at injection site
What are the Adverse Effects
Adverse Reactions
Tachycardia, palpitations, hypoglycemic reaction
Shock, anaphylaxis, ketoacidosis(fruity odor of breathe)
INSULIN SIDE EFFECTS
ADVERSE REACTIONS
Should you take insulin with beta blockers?
Interactions
Decreased glucose with aspirin, oral anticoagulants,
alcohol, other hypoglycemics, Beta blockers
Increased glucose with thiazides, glucocorticoids,
oral contraceptives, thyroid drugs, smoking
Contraindications
Hypoglycemia
Allergy
What are the 5 types of Insulin?
Rapid-acting
Short-acting
Intermediate-acting
Long-acting
Combinations NPH 70/30 REGULAR
RAPID ACTING INSULIN
Insulin lispro (Humalog)
Onset of action (15-30 minutes)
Peak (30 minutes to 90 minutes)
Duration (3 to 5 hours)
TAKE WITH FOOD , MEAL TRAY
SHORT ACTING INSULIN
Short-acting insulin (clear)
Insulin Regular
Onset of action (30 minutes)
Peak (1.5 to 3.5 hours)
Duration (4 to 12 hours)
INSULIN TYPES
INTERMEDIATE ACTING INSULIN
Intermediate-acting (cloudy)
NPH Insulin
Onset of action (1 to 2 hours)
Peak (4 to 12 hours)
Duration (14 to 24 hours)
LONG ACTING INSULIN
Long-acting
Insulin glargine
* Onset of action (1 to 1.5 hours)
* Duration (24 hours)
* Administered at bedtime
INSULIN TYPES
COMBINATION INSULIN
Combinations
Composed of short- and intermediate-acting or rapid- and intermediate-acting
Humulin or Novolin 70/30 (NPH 70%, insulin regular 30%)
NPH 50%, regular 50%
Can be mixed in other strengths
What is the most important instruction for a pt using an insulin pen?
prime the insulin pen needle first before use
Should you only use the abdomen when administrating insulin
NO
rotate sites to prevent lipodystrophy (causes damage to adipose tissue, which prevents proper fat storage. )
What is Sliding Scale Insulin used for?
Sliding-scale insulin coverage
Adjusted doses dependent on individual blood
glucose
Usually done before eating and at bedtime
Usually uses rapid or short-acting insulin
Example
151-200 2 units insulin lispro
201-250 4 units insulin lispro
251-300 6 units insulin lispro
301-350 8 units insulin lispro