UNIT 10 Glycopeptide

Question 1

What drug class is Vancomycin?

A. NSAID
B. Anticoagulants
C. Glycopeptide
D.Macrolide

Answer 1

C. Glycopeptide

Question 2

Should you obtain a Culture and Sensitivity test before administering Vancomycin?

A. Yes
B. No

Answer 2

Yes

Question 3

Are peak and trough lab values used for Antibiotic medications ?
A. No
B. Yes

Answer 3

B. Yes

Question 4

When are Peak labs drawn for an IV medication?
A. 30-60 minutes after drug administration
B. 1 hour - 2 hours after drug administration
C. immediately after drug administration
D. immediately before the next dose of a medication

Answer 4

A. 30-60 minutes after drug administration

If the drug is given intravenously, the peak time is usually 30 to 60 minutes after the infusion is complete.

If the drug is given intramuscularly, the peak time is usually 2 to 4 hours after injection.

If the drug is given orally, the peak time is usually 2 to 3 hours after drug administration.

Question 5

When would you pull a Trough lab when a patient has been receiving antibiotic medication?
A. immediately before the next dose of drug regardless of route of administration.
B. just after the next dose of drug regardless of route of administration.
C. 30 -60 minutes after drug administration
D. 1 hour before the next dose of the antibiotic medication

Answer 5

A. immediately before the next dose of drug regardless of route of administration.

The trough drug level is the lowest plasma concentration of a drug, and it measures the rate at which the drug is eliminated. Trough levels are drawn just before the next dose of drug regardless of route of administration.

Question 6

What is the use of VANCOMYCIN?

Answer 6

Started in the 1950’s
* Serious infections
* MRSA
* Bacteria have developed a resistance to this drug (VRE)

Question 7

If given Vancomycin Intravenously should you push slowly?

A. Yes
B. No

Answer 7

A. Yes

Given
* Oral
* IV – slowly

Question 8

What are the side effect of Vancomycin?

Answer 8

Chills, dizzy
* GI distress
* Thrombophlebitis (given in a central line IV- Thrombophlebitis is a swollen or inflamed vein due to a blood clot.

Question 9

What are the adverse effects of Vancomycin?

Answer 9

*Nephrotoxic
* Ototoxic
* Can lead to permanent hearing loss because of cranial
nerve damage(CRANIAL NERVE 8)
* Can lead to permanent loss of balance
* Stevens Johnson syndrome

Question 10

Is red man syndrome closely related to an effect that Vancomycin causes?

A. Yes
B. No

Answer 10

A. Yes

Red-man syndrome – giving it too fast can cause a
rash to face, neck, back, and chest - toxic effect

Other symptoms can include hypotension,
tachycardia, wheezing, and sometimes itching

Question 11

Nursing Interventions for Vancomycin

Answer 11

Nursing interventions
Obtain C&S before therapy.
Monitor vancomycin levels (peak and trough)
Administer over 1 to 2 hours IV.
Monitor BP.
Monitor IV site. – usually a central line
Monitor renal function tests including creatinine
clearance as ordered on renal patients
Hearing.
Monitor patient for superinfection.

Question 12

A patient is ordered to receive vancomycin for a
severe infection. It is most important for the
nurse to assess the patient for the development
of
A. neurotoxicity.
B. hepatotoxicity.
C. ototoxicity.
D. cardiotoxicity

Answer 12

Answer: C
* Rationale: Vancomycin may cause nephrotoxicity and
ototoxicity. Ototoxicity results in damage to the
auditory or vestibular branch of cranial nerve VIII.
Such damage can result in permanent hearing loss
(auditory branch) or temporary or permanent loss of
balance (vestibular branch).