UNIT 11 Estrogen Replacement

Question 1

What is the drug class of Conjugates Estrogen?

A.Antithyroid
B. Estrogen replacement
C. Opiod
D. NSAID

Answer 1

B. Estrogen replacement

Question 2

What is Menopause

Answer 2

Transitional process experienced by women
as they move from the reproductive years into
the non-reproductive stage of life

Question 3

What is needed for reduce the symptoms of menopause?

Answer 3

Conjugated Menopause

Question 4

What is the action of Congucated Estrogen?

Answer 4

Use
– To minimize symptoms of menopause
■ Action
– Replaces the hormone estrogen

Question 5

What are some symptoms of Menopause?

Answer 5

– Hot flashes
– Vaginal dryness
– Sleep disorders
– Headaches
– Irritability
– Anxiety or other variations in mood
– Cognitive difficulties
– Memory lapses
– Joint aches
– Decreased libido

Question 6

A patient who’s been diagnosed with Menopause, has not had a hysterectomy. Should they be prescribed estrogen?

A. No
B. Yes

Answer 6

A. No

THEY WILL DEVELOP CANCER 100%

Hormone replacement of estrogen is only used for women who has had a hysterectomy

Estrogen therapy (ET) for use with
women who have had a hysterectomy
(surgical removal of the uterus)

Boxed warning—hormone therapy should be
used only for the treatment of menopausal
symptoms, at the lowest dose possible, for the
shortest duration possible, usually less than 5
years.

No use by women with hx of MI, new primary
malignancy, stroke, DVT/PE, dementia

Question 7

What is the typical duration of Estrogen therapy for pt’s with Menopause?

A. less than 5 years
B. less than 10 years
C. Less than 3 months
D. Less than 10 months

Answer 7

A. less than 5 years

Boxed warning—hormone therapy should be
used only for the treatment of menopausal
symptoms, at the lowest dose possible, for the
shortest duration possible, usually less than 5
years.

Question 8

Contraindications of Estrogen

Answer 8

Pregnancy, undiagnosed vaginal bleeding
■ Acute liver disease or chronic impaired liver function
■ Personal history of breast cancer/endometrial cancer
(black box warning)
■ History of thromboembolic disorders (DVT) (black box
warning
■ Active gallbladder or pancreatic disease
■ Coronary artery disease (CAD)
■ Endometriosis
- bleeding that is undiagnosed

No use by women with hx of MI, new primary
malignancy, stroke, DVT/PE, dementia

Question 9

Interactions of other drugs with Estrogen

Answer 9

Interactions
– Corticosteroids – increases effect of
estrogen
– Anticoagulants – decreases effects of
anticoagulants
– Hypoglycemics – decreases effects of
hypoglycemics

Question 10

Can estrogen increase blood sugar or blood glucose?

A. No
B. Yes

Answer 10

B. Yes

Question 11

Side effects of Estrogen

Answer 11

• fluid retention
  -Breakthrough bleeding,
• breast tenderness

Question 12

Can Estrogen increase blood cots formation

A. No
B. Yes

Answer 12

B. Yes

Question 13

Adverse effect of Estrogen

Answer 13

Jaundice
DVT
depression
Gallbladder disease
CVA, PE, MI, endometrial cancer

Question 14

The nurse identifies which condition as a
contraindication to hormone replacement
therapy?
A. Diabetes mellitus
B. Depression
C. Renal failure
D. Breast cancer within the last 5 years

Answer 14

Rationale: A history of endometrial or breast cancer withinthe last 5 years is a contraindication for hormone
replacement therapy, as are pregnancy, history of
thromboembolic disorders, acute liver disease or chronic impaired liver function, gallbladder or pancreatic disease,
poorly controlled hypertension, undiagnosed genital
bleeding, and endometriosis