UNIT 11 Ethrypoetin Stimulating Agent

Question 1

Is Epoetin a replacement of blood transfusion

A. Yes
B. No

Answer 1

A. Yes

Action
 Increases production of RBC’s within the bone marrow.(MOE HEMOGLOBIN)
 Increases oxygen carrying blood cells

 Uses
 Treats anemia secondary to chronic renal failure or
chemotherapy
 Prevent use of blood transfusion

Question 2

Side effect of Epoetin?

Answer 2

 Injection site reaction
 Headache, muscle pain, joint pain

Question 3

Adverse effect of Epoetin

Answer 3

 Allergic reaction, mild-severe
 Hypertension
 MI, stroke

Question 4

The patient’s Hemoglobin is 30 Is there a candidate for Epoetin?

A. No
B.Yes

Answer 4

A. No

you must monitor the patient HGB levels before administering Emotion, andministing Emotion with this patients HGB can cause blood clots or strokes or MI.

YOU NEVER ADMINISTER EPOETIN IF THE HEMOGLOBIN IS 11 OR MORE

Question 5

What are the contraindications for Epoetin?

Answer 5

Contraindications
 Uncontrolled hypertension
 Allergy
 Increased hematocrit
 Caution with hemoglobin levels over 11 – at risk for
cardiovascular or thromboembolic events
 Black box warning – if hemoglobin over 11, hx MI, stroke,
patient with cancer, increased risk of embolism have an
increased risk of death with this drug

 Interactions
 Androgens increase effect

Question 6

can Epoetin cause hypertension , is this a normal finding?

A. Yes
B. No

Answer 6

B. No

Hypertention is an adverse effect

Question 7

Nursing Intervention for Filgrastim and Epoetin

Answer 7

Nursing interventions
 Monitor patient for side effects focusing on vitals signs, fluid
balance, DVT, cardiac, respiratory
 Increase fluids to 2L day
 Monitor for signs and symptoms of anemia (epoetin alfa) and
plan care accordingly. Monitor for SE/AR
 Monitor for signs and symptoms of infection (filgrastim) and plan care accordingly. Monitor for SE/AR

 Evaluation
 Epoetin Alfa – increase in RBC’s
 Filgrastim – No s/s of infection

Question 8

How do you know that Epoetin worked?

Answer 8

increased in red blood cell

Question 9

When working with a patient receiving epoetin alpha, it is
most important for the nurse to assess the patient for the
development of
a. bone pain and headaches.
b. hypertension and edema.
c. nausea and vomiting.
d. fluid retention and allergic reactions

Answer 9

b. hypertension and edema.

Question 10

Before administering epoetin alpha, it is most important for
the nurse to assess the patient for a history of which
condition?
a. Anemia
b. Chronic renal failure
c. Pancreatitis
d. Hypertension

Answer 10

d. Hypertension

Answer: D
 Rationale: Erythropoietin-stimulating agent administration is
contraindicated in patients with (1) uncontrolled hypertension, (2)
known hypersensitivity to mammalian cell–derived products, and
(3) known hypersensitivity to human albumin or polysorbate.
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