ANTIPLATELETS UNIT 6 CHAPTER 40

Question 1

Which of the following drugs is Antiplatelet? SELECT ALL THAT APPLY

A. Clopidogrel
B. Phenelizine
C. Valproic Acid
D. Aspirin

Answer 1

D. Aspirin
A. Clopidogrel

Antiplatelets
 Prevent platelet aggregation – aspirin and clopidogrel

Question 2

Aspirin Action

Answer 2

Aspirin
 Effective and inexpensive treatment for suppressing
platelet aggregation
Low-dose therapy
Action
Inhibit platelet aggregation by inhibiting COX 1
Use
 Prevention of MI and stroke
 Refer to unit 2 to review aspirin
ANTIPLATELET DRUGS
ASPIRIN

Question 3

Should you give Aspirin to a Patient with a history of peptic ulcers?

A. No
B. Yes

Answer 3

A. No

Blocks COX 1 which protects the stomach lining and regulates platelet aggregation

Question 4

What is the use of ASPIRIN, is it mainly to prevent blood clots or get rid of blood clots ?

Answer 4

To prevent blood clots

 Effective and inexpensive treatment for suppressing
platelet aggregation
Low-dose therapy
Action
Inhibit platelet aggregation by inhibiting COX 1
Use
 Prevention of MI and stroke
 Refer to unit 2 to review aspirin
ANTIPLATELET DRUGS

Question 5

Action of CLOPIDOGREL BISULFATE

Answer 5

Action CLOPIDOGREL BISULFATE
 Suppress platelet aggregation.
 Used
 Prevent thrombosis in the arteries
 Prevention of myocardial infarction or stroke for patients
with familial history
 Prevention of a repeat myocardial infarction or stroke
 Prevention of a stroke for patients having transient
ischemic attacks
ANTIPLATELETS

Question 6

Sid effect and adverse effect of CLOPIDOGREL BISULFATE

Answer 6

Side Effects
Abdominal pain, dizziness, confusion, epistaxis, headaches, hematoma, dyspepsia, diarrhea, constipation, purpura, peripheral edema, rash, pruritus

ADVERSE
Hypotension, hypertension, bronchospasm, bleeding, peptic ulcer, intracranial/GI bleeding

Question 7

Contraindications of CLOPIDOGREL BISULFATE

Answer 7

Intracranial hemorrhage,
GI bleeding
Caution:
Hepatic/renal disease, surgery, peptic ulcer, thrombotic thrombocytopenia trauma, older adults, pregnancy, breastfeeding

 Contraindications
 Bleeding
 Peptic ulcer
 Caution
 Liver disease
 Renal disease
Interactions
Other drugs that cause bleeding
4 G’s
ANTIPLATELETS
CLOPIDOGREL BISULFATE

Question 8

4. The nurse is teaching a patient about clopidogrel. Which information will the nurse include in the patient’s teaching plan?
   a. Constipation may occur.
   b. Hypotension may occur.
   c. Bleeding may increase when taken with aspirin.
   d. Normal dose is 25-mg tablet per day.

Answer 8

c. Bleeding may increase when taken with aspirin.

Question 9

8. Cilostazol is being prescribed for a patient with coronary artery disease. The nurse understands that which of the following is the major purpose for antiplatelet drug therapy?

a. Dissolve the blood clot
b. Decrease tissue necrosis
c. Inhibit hepatic synthesis of vitamin K
d. Suppress platelet aggregation

Answer 9

d. Suppress platelet aggregation

Question 10

A patient is prescribed aspirin, 81 mg, and
clopidogrel. The nurse identifies the drug
classification of clopidogrel as
A. anticoagulant.
B. thrombotic inhibitor.
C. antiplatelet.
D. thrombolytic.

Answer 10

ANS: C
Clopidogrel is an antiplatelet drug.