UNIT 11 Antiemetic- Phenothiazine

Question 1

What drug class is Prometheazine?

Answer 1

Antiemetic- Phenothiazine

Question 2

What is the action of Promethazine

Answer 2

Prescriptive antihistamines/antiemetic
 Many available – think of route
 Promethazine
Action
 Blocks histamine 1 & dopamine receptor sites
to CTZ
Uses
 Treats and prevents motion sickness, nausea,
and vomiting

Question 3

Side effect of Promethazine

Answer 3

Side effects/adverse reactions
 Drowsiness, dry mouth and eyes
 Photosensensitivity
 Urinary retention/constipation

Question 4

Adverse effect of Promethazine

Answer 4

EPS
 Respiratory depression

Question 5

Does promethazine have anticholinergic effects?

Answer 5

Yes

Caution
 Glaucoma
 Liver disease, asthma, hypertension,
 Older adults
 Debilitated patients
 Interactions
 Other CNS depressants, alcohol
 False pregnancy test

Question 6

Is Promethazine an CNS depressant?

Answer 6

Yes