UNIT 8 Leukotriene Modifier CHAPTER 38

Question 1

What is the drug class of Montelukast?

Answer 1

Leukotriene

Question 2

What is the action of Montelukast?

Answer 2

Action
 Binds with leukotriene receptors to reduce inflammatory process and bronchoconstriction
 Uses
 Prevention of exercise-induced bronchospasm and maintenance treatment of asthma

used 30 min-1hr before excersize

Question 3

Side effect of Montelukast

Answer 3

Side effects/adverse reactions
 Headache, drowsiness, Restlessness, insomnia,
confusion

Question 4

Adverse effect of Monetlukast

Answer 4

 Hepatotoxic
 Bleeding
 Suicidal ideation

Question 5

Contraindications of Montelukast

Answer 5

Contraindications
 Severe asthma attack
 Caution
 liver disease
 Suicidal

 Interactions
 Can increase liver function tests
 Anticoagulants
 aspirin, ibuprofen (cause bleeding and Block drug
action)

Question 6

Nursing Intervention & Pt teaching for Montelukast

Answer 6

Leukotriene receptor
antagonist - Montelukast
 Interventions/teaching
 Monitor vs, breath sounds
 Observe for side effects/adverse reactions
 Increase fluids to thin secretions
 Monitor lft’s
 Do not take with anticoagulants and aspirin,
ibuprofen
 Teach to stop smoking
 Teach its use is to prevent attacks – do not take
during an attack
 Inform hcp if dyspnea increases
 Take medication daily in the evening (asthma
symptoms usually worse at night)

Question 7

The nurse is preparing class for patients with
asthma. The nurse will inform the patients that
leukotriene modifiers are used in the treatment of
asthma to
A. assist in opening narrowed airways.
B. suppress the release of histamine and other mediators
from the mast cells.
C. loosen mucus from the airways.
D. prevent serious complications from bacterial infections.

Answer 7

Answer: B
 Rationale: Leukotriene modifiers are used in the treatment of patients with asthma
to suppress the release of histamine and other mediators from the mast cells. In
the treatment of patients with COPD, bronchodilators such as sympathomimetics,
parasympatholytics, and methylxanthines are used to assist in opening narrowed
airways; expectorants are used to loosen mucus from the airways, and antibiotics
may be prescribed to prevent serious complications from bacterial infection.