UNIT 9 Antithyroid CHAPTER 49

Question 1

Propylthiouracil

Answer 1

NCREASE IN CIRCULATING T4 AND T3 LEVELS
 GRAVES DISEASE, OR THYROTOXICOSIS
* SIGNS AND SYMPTOMS
* TACHYCARDIA, PALPITATIONS, EXCESSIVE PERSPIRATION,
HEAT INTOLERANCE, NERVOUSNESS, IRRITABILITY,
EXOPHTHALMOS (BULGING EYES), AND WEIGHT LOSS
 TREATMENT
 ANTITHYROID DRUGS, WHICH INHIBIT EITHER
SYNTHESIS OR RELEASE OF THYROID HORMONE
* SURGICAL REMOVAL OF A PORTION OF THE THYROID
GLAND (SUBTOTAL THYROIDECTOMY)
* RADIOACTIVE IODINE THERAPY

Question 2

Action of Propylthiouracil

Answer 2

ACTION
 REDUCE THE EXCESSIVE SECRETION OF
THYROID HORMONES (T3 AND T4)
 USES
 HYPERTHYROIDISM
CAN TAKE A WEEK TO WORK
MAY NEED BETA BLOCKER (PROPRANOLOL-
DRUG OF CHOICE FOR HYPERTHYROIDISM TO
CONTROL BP & HR)

Question 3

Interactions of Propylthiouracil

Answer 3

INTERACTIONS
* INCREASE EFFECT OF ANTICOAGULANTS
* DECREASE EFFECT OF ANTIDIABETICS
* DIGOXIN AND LITHIUM INCREASE ACTION OF THYROID
DRUGS.

• SIDE EFFECTS/ADVERSE REACTIONS
• SORE THROAT
• RASH
• FEVER
  .

Question 4

Nursing Interventions/ Patient teaching

Answer 4

NURSING INTERVENTIONS
 MONITOR VITAL SIGNS, WEIGHT.
 ADMINISTER THYROID REPLACEMENT
DRUG BEFORE BREAKFAST ON EMPTY
STOMACH
 TAKE ANTITHYROID DRUG WITH MEALS
 CHECK LABELS BEFORE USING OTC’S.
 ADVISE REPORTING OF SYMPTOMS OF
HYPERTHYROIDISM/HYPOTHYROIDISM
 ENCOURAGE MEDICAL ALERT TAG.
THYROID CONDITIONS

NURSING INTERVENTIONS
 DO NOT ABRUPTLY STOP THYROID DRUGS.
 ADVISE REPORTING OF SYMPTOMS OF
HYPOTHYROIDISM/HYPERTHYROIDISM
 TAKE DRUG SAME TIME EVERY DAY
 TEACH PATIENT TO TAKE VITAL SIGNS
 TEACH DIABETIC PATIENT THAT THYROID
DRUGS CAN DECREASE EFFECTIVENESS
OF ANTIDIABETIC DRUGS
THYROID CONDITIONS (CONT.)