Nitroimidazole/Antiba cterial peptide UNIT 10

Question 1

use of Metronidazole

Answer 1

Used for some GI (H. Pylori) or GU (STI’S)
issues
* Teaching
Avoid alcohol
* Disulfiram-type reaction: facial flushing, sweating, severe
headache, slurred speech
To side effects with high doses
Dark urine or reddish brown
Metallic or bitter taste
GI distress
Superinfection
Peripheral neuropath

Question 2

side effect

Answer 2

Anorexia, nausea, dry mouth, metallic taste, headache, dizziness, vomiting, diarrhea, abdominal cramps

Question 3

adverse effect

Answer 3

Seizures, aseptic meningitis, pseudomembranous colitis, pancreatitis leukopenia, bone marrow suppression, aplasia, thrombocytopenia, Stevens-Johnson syndrome, toxic epidermal necrolysis