UNIT 10 Macrolide

Question 1

What is the drug class of Azithromycin?

A. Macrolide
B. Biguinide
C.Non Opiod Analgesic
D. Loop diuretic

Answer 1

A. Macrolide

Question 2

Is Azithromycin an Antibiotic?

A. Yes
B. No

Answer 2

A. Yes

Question 3

What is the use of Azithromycin?

Answer 3

Used when patients are allergic to PCN/Cephalosporins
* For stronger bacterial infections

Question 4

What are the side effects of Azithromycin

Answer 4

*Blurred vision,
*headache,
*drowsy,
*fatigue
* GI distress
* Photosensitivity

Question 5

What is An Adverse effect of Azithromycin?

Answer 5

Allergic reaction/anaphylaxis
* Tinnitus - ototoxicity
* Superinfection
* Hepatotoxicity
* Stevens-Johnson syndrome

Question 6

The pt has devalued a large red rash all across his chest while taking a Macrolide. What is the next appropriate action for the nurse to take?
A. Administer diphenhydramine since this is a mild allergic reaction
B. Immediately stop the medication and contact the HCP
C. Wait until this dose is done to hold the next dose
D. This is a normal finding

Answer 6

B. Immediately stop the medication and contact the HCP

Steven Johnson Syndrome is an adverse effect of this medication and must be stopped immediately

stevem Johnshon- a rare serious disorder of the skin It’s usually a reaction to medication that starts with flu-like symptoms, followed by a painful rash that spreads and blisters. Then the top layer of affected skin dies, sheds and begins to heal after several days.

Question 7

Containdidcations for Azithromycin

Answer 7

Allergy
* Heart issues (dysrhythmias)
* Hepatic/Renal dysfunction

Interactions
Levels of warfarin increase.
Levels of digoxin increase
Oral birth control

Question 8

Do all antibiotics increase the risk for bleeding when paired with anticoagulants?

A. No
B. Yes

Answer 8

B. Yes

Question 9

Is Azithromycin Toxic to the Liver
‘
A. No
B. Yes

Answer 9

B. Yes

can also cause tinitis(ringing of the ear) and ototoxicity

Assessment
* Vital signs
* I & O; urinary output
* Check labs for liver/kidney function
* Drug history
* Medical history

Question 10

Nursing Intervention of Azithromycin

Answer 10

Nursing interventions
Obtain culture and sensitivity (C&S) before therapy.
Monitor vital signs & urine output
Monitor liver enzymes and for S/S of liver issues
Monitor for superinfection
Administer antacids 2 hours before or 2 hours after
macrolides.
Give azithromycin 1 hour before or 2 hours after meals
with full glass of water – no fruit juice
Use sunscreen
Ok to give with food with stomach upset

Question 11

When would you Obtain Culture and Sensitivity test?

A. before any medications given to the patient
B. 30-60minutes are Cephalosporin is given
C. never
D. after the broad spectrum antibiotic is given

Answer 11

A. before any medications given to the patient

Question 12

Azithromycin Teaching

Answer 12

• Take full course of treatment
• Teach to expected side effects and how to
  manage
• Teach to adverse reactions that need reported
  to HCP, including signs and symptoms of
  Pseudomembranous colitis (C. Diff)

Question 13

Which teaching by the nurse has highest priority for the
patient taking azithromycin?
A. Instruct the patient to use sunblock and protective
clothing during sun exposure.
B. Instruct the patient to store the drug out of light and
extreme heat.
C. Inform parents that children younger than 8 years
should not take the drug, to avoid tooth
discoloration.
D. Instruct the patient to report any loose stools or
diarrhea.

Answer 13

D. Instruct the patient to report any loose stools or
diarrhea. (sign of adverse reaction of Azithromycin)

The patient should be instructed to report
loose stools or diarrhea because of possible
pseudomembranous colitis. Photosensitivity during
sun exposure is common with tetracyclines, which
should not be given to children younger than 8 years;
the drugs are affected by light and extreme heat