Unit 8 - Prostate Cancer Flashcards
Prostate cancer is curable when…
diagnosed early
_____ out of _____ men are diagnosed with prostate cancer in their lifetime
1 out of 8
_____ out of ______ men will develop invasive prostate cancer by age 60 or older
1 out of 19
What is the 3rd leading cause of cancer-related death in US
prostate cancer
Prostate cancer may compress urethra -> _____ _____ _____
obstructing urinary flow
Prostate cancer:
metastasis: _____ and _____
lymph & venous channels
Greatest risk factor of prostate cancer
age (disease of older men)
Several mutated genes have been found that may be responsible for a man’s inherited tendency to develop prostate cancer. One of these is called _____ (_____ _____-_____ _____ _____ _____ _____). But there are many other gene mutations that may account for some cases of hereditary prostate cancer. None of these is a major cause, and more research on these genes is being done. Genetic tests are not yet available.
Men with _____ or _____ gene changes may have an increased prostate cancer risk. Mutations in these genes more commonly cause _____ and _____ cancer in women. But inherited BRCA changes probably explain only a very small number of _____ cancers.
RNASEL formerly HPC1 -Hereditary Prostate Cancer Gene 1 BRCA1 BRCA2 breast ovarian prostate
_____ to prevent prostate cancer are the topic of research
medications
Hormones used to treat benign prostatic hyperplasia show a _____% reduction of risk
25%
Initiate discussion of prostate cancer for men at age _____
50
African Americans and any whose close relative was diagnosed before age 60 -> initiate discussion at age _____
45
For men at even higher risk (those with several close relatives diagnosed at an early age) -> initiate discussion at age _____
40
early-stage prostate cancer is usually _____
asymptomatic
5 urinary manifestations of prostate cancer
- urgency
- frequency
- hesitancy
- dysuria
- nocturia
_____ in the ejaculate is a manifestation of prostate cancer
hematuria
_____ from metastasis to bones is often the initial manifestation
pain
Definitive diagnosis of prostate is by _____
biopsy
_____ is used to guide needle biopsy of prostate cancer
ultrasonography
_____ _____ _____ (DRE) -> prostate gland nodular, fixed
Digital rectal examination (DRE)
_____-_____ _____ (PSA) -> used to diagnose, stage prostate cancer and monitor response to tratment
Prostate-specific antigen (PSA)
PSA is used with _____
DRE
_____ _____, _____, _____ -> to determine presence of metasases
Bone scan, MRI, CT
Grade and stage help determine _____, guide treatment decisions
prognosis
No routine screenings are endorsed because of the concern of a possible high rate of _____-_____ (detecting disease that would never have caused symptoms), along with serious side effects from prostate cancer treatment.
over-diagnosis
Are there routine prostate cancer screening guidelines for men at average risk at this time?
Not at this time
Screening for prostate cancer can be done with:
- _____ _____ _____ (_____) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the _____ gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- _____ is less effective than the PSA blood test in finding prostate cancer, but it can sometimes find cancers in men with normal PSA levels.
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal - PSA levels.
Screening for prostate cancer can be done with:
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- _____-_____ _____ (_____) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal - PSA levels.
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal - PSA levels.
Screening for prostate cancer can be done with:
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of _____ [less than _____ nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal - PSA levels.
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal - PSA levels.
Screening for prostate cancer can be done with:
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- _____ is less effective than the PSA blood test in _____ prostate
cancer, but it can sometimes find cancers in men with normal - PSA levels.
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal - PSA levels.
Screening for prostate cancer can be done with:
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal _____ levels.
- Prostate-Specific Antigen (PSA) blood test with or without a Digital Rectal Exam (DRE)
- Prostate-specific antigen (PSA) /Made by cells in the prostate gland
- Most healthy men have a small amount of PSA [less than 4 nanograms per milliliter (ng/mL)] in their blood
- DRE is less effective than the PSA blood test in finding prostate
cancer, but it can sometimes find cancers in men with normal PSA levels.
Transrectal ultrasonography-guided biopsy:
- _____ _____ inserted via rectum to lie adjacent to the _____
- _____ _____ biopsy needle to the prostate tissue
- Tissue sample taken from _____/means of a hollow needle that is advanced and withdrawn by _____ _____ _____
- Ultrasound probe inserted via rectum to lie adjacent to the prostate
- Image guided biopsy needle to the prostate tissue
- Tissue sample taken from prostate/means of a hollow needle that is advanced and withdrawn by pulling a ‘trigger’
Gleason Grading:
- system defines the type of tissue from which the tumor _____ and the degree of tumor cells _____ their relationship to their _____ tissue
- graded from _____ to _____
- system defines the type of tissue from which the tumor originated and the degree of tumor cells retain their relationship to their original tissue
- graded from I to IV
Suprapubic prostatectomy:
- clients with stage III locally advanced -> surgery is _____, may be used to _____ _____
- clients with stage III locally advanced -> surgery is controversial, may be used to relieve obstrction
Prostatectomy:
- surgical intervention available for men with post prostatectomy incontinence due to…
urinary sphincter insufficiency
Androgen deprivation therapy:
- used to treat _____ _____ _____
- strategies to induce androgen deprivation include _____, administration of _____ _____
advanced prostate cancer
orchiectomy, hormonal agents
Radiation therapy:
- may be used as primary treatment -> _____ risk of long-term problems of _____, urinary incontinence associated with _____
- also in palliative role for clients with _____ _____
reduces
impotence
surgery
metastatic cancer
Diagnosis for prostate cancer:
- impaired _____ _____
- risk for urinary _____
- risk for stress urinary _____
- _____ dysfunction
- _____
- impaired urinary elimination
- risk for urinary retention
- risk for stress urinary incontinence
- sexual dysfunction
- pain
Promote urinary elimination:
- assess the degree of _____ and its effects on lifestyle
- teach _____l exercises to help restore _____
- teach methods to control _____ and _____ from stress incontinence
- _____ _____ attempt to prevent accidental voiding by restricting fluids
- mange occasional episodes with _____ _____ worn inside underwear and changed as needed
- refer to _____ _____ or a _____ specialist for additional measures
- explore options such as an _____ _____ _____
- encourage verbalizing feelings about impact of _____ on quality of life
- assess the degree of incontinence and its effects on lifestyle
- teach kegel exercises to help restore continence
- teach methods to control dampness and odor from stress incontinence
- do not attempt to prevent accidental voiding by restricting fluids
- mange occasional episodes with absorbent pads worn inside underwear and changed as needed
- refer to physical therapy or a continence specialist for additional measures
- explore options such as an external collection device
- encourage verbalizing feelings about impact of incontinence on quality of life
Promote communication related to _____ function
sexual
Surgical treatment may cause _____ _____
erectile dysfunction
Promote effective _____ management
pain
Planning:
- client verbalizes concerns about, symptoms of sexual dysfunction without _____
- client maintains adequate _____ output
- client lists strategies for reducing and coping with _____ _____
- client received adequate pain management to control pain within _____ levels
- client verbalizes concerns about, symptoms of sexual dysfunction without discomfort
- client maintains adequate urinary output
- client lists strategies for reducing and coping with urinary incontinence
- client received adequate pain management to control pain within tolerable levels
Evaluation of Prostate Cancer:
- client rates and reports pain before it becomes _____
- client discuses _____ _____ without anxiety or discomfort
- client list _____ for managing urinary incontinence
- client maintains adequate urine output without _____ related to altered urinary illumination
- client rates and reports pain before it becomes intolerable
- client discuses sexual function without anxiety or discomfort
- client list strategies for managing urinary incontinence
- client maintains adequate urine output without complications related to altered urinary illumination