Unit 3 - Chronic Kidney Disease Flashcards
Definition: little or no kidney function (5 stages)
end-stage renal disease (ESRD)
Definition: may progress for years unrecognized
Chronic Kidney Disease
Describe the early stage of Chronic Kidney Disease (Decreased renal reserve)
- unaffected nephrons compensate
- GFR: ~50% normal
- asymptomatic, normal BUN, creatinine
1 cause of CKD (Chronic Kidney Disease)
Diabetes Mellitus
What happens to creatinine levels in renal failure
rise sharply
*The damaged kidney is unable to excrete waste products, including creatinine
In ESRD:
_____ _____ _____ is necessary to sustain life
renal replacement therapy
Longstanding _____ leads to sclerosis and narrowing of renal arterioles and small arteries with subsequent reduction of blood flow. This leads to ischemia, glomerular destruction, and tubular atrophy.
hypertension
Diabetic ______ causes renal failure by thickening and sclerosis of the glomerular basement membrane and the glomerulus with a gradual destruction of nephrons.
nephropathy
_____ _____ _____ causes renal failure by multiple bilateral cysts gradually compressing renal tissue, impairing renal perfusion and leading to ischemia, which damages and destroys normal kidney tissue.
Polycystic kidney disease
_____ _____ _____ causes renal failure by the formation of immune complexes in the capillary basement membrane, which lead to inflammation and sclerosis
Systemic lupus erythematosus
_____ _____ are nearly 4 times as likely to develop kidney disease as Caucasians
African Americans
Prevention of end-stage renal disease should focus on aggressive management of chronic disease states, especially \_\_\_\_\_ (control blood glucose levels) and \_\_\_\_\_ (medication compliance)
In addition, clients should consume diets low in _____, exercise regularly, keep healthcare provider appointments, avoid _____, and limit _____ intake.
diabetes hypertension sodium smoking alcohol
What is uremia
urea in the blood
_____ is common in clients with renal disease. Among the factors causing the _____ are decreased production of erythropoietin by the kidneys and shortened red blood cell (RBC) life. Erythropoietin is involved in the stimulation of the bone marrow to produce RBCs. Metabolic wastes do not suppress the bone marrow
Anemia, anemia
______: The manifestations of renal failure often are missed in aging clients because _____ may be attributed to heart failure or high blood pressure to preexisting hypertension. (new hypertension may be an indicator of the disease)
Edema, edema
How are uric acid levels effected with CKD
increased -> gout
Describe BUN levels with CKD
increased due to damaged kidneys
Describe serum osmolality with CKD
increased, because damaged kidney is unable to excrete solutes
Describe urine osmolality with CKD
decreased, because damaged kidney is unable to excrete solutes
Describe Phosphorus and Potassium levels during renal failure
increase, due to inability of the kidney to excrete them
T/F: There is no medication provided to a client with chronic kidney disease that is used to stabilize protein levels in the body.
T
_____ is a loop diuretic that may be prescribed to reduce extracellular fluid volume and edema.
Furosemide (Lasix)