Unit 6 - Inflammation Flashcards
Defintion:
adaptive response to injury, illness that brings plasma, dissolves substances, blood cells into interstitial tissues where damage occurred
inflammation
Definition:
damaged cells, bacteria, exudate removed through phagocytosis
debridement
Is pallor a sign of inflammation
No, redness is
is pitting edema a sign of inflammation
No
6 signs of inflammation
- redness
- swelling
- warmth
- pain
- heat
- impaired function
4 S/S of systemic reaction
- fever
- increased pulse
- tachypnea
- leukocytosis (WBC > 12,000)
5 S/S of local reaction
- erythema
- warmth
- pain
- edema
- functional impairment
Describe the inflammatory process
- complex response of vascular tissues triggered by harmful stimuli
Stage 1 of inflammation
vascular and cellular responses
Stage 1 of inflammation:
- Blood vessels at site _____
- Inured tissues releases _____, _____, and _____
- Chemical mediators cause _____
- Vascular permeability _____
- Fluid, proteins, and leukocytes…
- Leukocytes -> …
- Leuko_____
- Blood vessels at site constrict
- Inured tissues releases histamines, kinines, and prostaglandins
- Chemical mediators cause hypermia
- Vascular permeability increases
- Fluid, proteins, and leukocytes leak into interstitial spaces causing edema and pain
- Leukocytes -> margination, emigration
- Leukocytosis
In the presence of an attack such as an infection, _____ WBCs are released from the bone marrow, and as WBCs move out of the bone marrow into the blood, the bone marrow (increases/decreases) its production of additional leukocytes, leading to _____.
additional
increases
leukocytosis
Instructing the client on the use of _____ razor and _____ toothbrush and assessing for bleeding and bruising would be appropriate actions for a client with decreased platelet levels, or thrombocytopenia.
electric
soft
T/F: placing a patient in reverse isolation precautions would be appropriate for the client with neutropenia
T
Defintion:
a decrease in the number of neutrophils
Neutropenia
Stage 2 of inflammation:
exudate production
- serous
- purulent
- hemorrhagic
Stage 3 of inflammation:
reparative phase
- regeneration
- fibrous tissue formation
2 parts to fibrous tissue formation:
- granulation tissue
- cicatrix
rapid release of inflammation mediators ->
anaphylaxis
Histamine and heparin work together to…
increase blood flow to injured site
- H1 and H4 receptors involved in inflammatory response
As a person grows older, there is an overall _____ in the speed and strength of the immune response
decrease = there is a decrease in the number of B cells in circulation
Describe healthy inflammatory response
activation and recruitment of WBCs to the affected site
Typical onset of rheumatoid arthritis
middle age with increased incidence among older adults
- also occurs in children and young adults
_____ or _____ Americans have increased risk for gallstone
Native or Mexican Americans
_____ _____ are more likely than caucasians to develop nephritis as a result of lupus
African Americans
Restricting fluids could cause respiratory secretions to…
thicken and hinder the client’s ability to maintain a clear airways = fluids should be encouraged
Modifiable Risk Factors: Crohn Disease: - Diet \_\_\_\_\_ in refined sugars - \_\_\_\_\_ fiber intake - smoking \_\_\_\_\_
Diet low in refined sugars
- increased fiber intake
- smoking cessation
Modifiable Risk Factor for Gallstone formation:
- _____ an appropriate weight
- diet _____ in fiber and _____ in fat
- _____ rapid weight loss
- maintain an appropriate weight
- diet high in fiber and low in fat
- avoid rapid weight loss
What affect do NSAIDS have on kidneys
nephrotoxic
T/F: keeping the client well hydrated will help prevent kidney damage
T
taking medication with food will _____ GI irritation
decrease, however preventing kidney damage is more of a priority