Unit 11 - DM Flashcards
the way our bodies use digested food for energy
metabolism
disorder of metabolism =
diabetes
Most of the food we eat is broken down into ____
glucose
_____ is the body’s main source of fuel
glucose
- after digestion, glucose enters the _____
- then it goes to cells through the body where it is used for _____
- However, a hormone called _____ must be present to allow glucose to enter the cells
- Insulin is a hormone produced by the _____
- bloodstream
- energy
- insuline
- pancreas
In people who do not have diabetes, the pancreas automatically produces the right amount of insulin to move glucose from blood into the cells. However, _____ develops when the pancreas does not make enough insulin, or the cells in the muscles, liver, and fat do not use insulin properly, or both. As a result, the amount of glucose in the blood _____ while the cells are _____ of energy. Resulting in _____
- diabetes
- increases
- starved
- hyperglycemia
T/F: Over time, high blood glucose levels damage nerves and blood vessels, leading to complications
T
Functions of insulin:
- Transports and metabolizes _____ for energy
- Stimulates storage of glucose in the _____ and muscle as _____
- Signals the liver to _____ the _____ of glucose
- Enhances storage of _____ in adipose tissue
- Accelerates transport of _____ _____ into cells
- Inhibits the breakdown of stored _____, _____, and _____
- Transports and metabolizes glucose for energy
- Stimulates storage of glucose in the liver and muscle as glycogen
- Signals the liver to stop the release of glucose
- Enhances storage of fat in adipose tissue
- Accelerates transport of amino acids into cells
- Inhibits the breakdown of stored glucose, protein, and fat
pancreas produces _____
hormones
alpha cells of the islet cells
glucagon
beta cells of the islet cells
insuline
delta cells of the islet cells (also in stomach/intestine)
somatostatin
T/F: pancreas is now being used in synthetic form to treat type 2
T
_____ is a peptide hormone of 37 amino acids, which is also secreted by the beta cells of the pancreas
amylin
amylin inhibits secretion of _____, slows the _____ of the stomach, and sends signal to the _____
glucagon
emptying
brain
all of amylin’s actions tend to supplement those of _____, reducing level of glucose in the blood
insulin
CDC 2014 Stats:
_____ developed diabetes at lower BMIs than _____…_____ may be more likely to develop type 2 diabetes than women
Men, women
Men, women
What compounds the female predicament is that _____ _____ is more deadly in women with diabetes than it is in men with the disease.
heart disease
_____ _____/_____ _____ have the highest significance
American Indians/Alaska Natives
Type 1 or 2:
the client is unable to obtain the needed glucose for the body’s cells, due to lack of insulin
type 1
Patients diagnosed with type _____ DM experience polyphagia, and are often thin…Although it is not impossible for Type _____ diabetics to gain weight
Type 1
Type 1
components in blood or tissue samples that can be measured to predict which individuals are most likely to develop Type 1 diabetes
biomarkers
Type _____ is thought to progress without symptoms for several years in most patients prior to diagnosis
Type 1
Type 1 or 2:
autoimmune disorder/destruction of pancreatic B cells
Type 1
Type 1 is the destruction of pancreatic _____ cells
B
Type 1 or 2:
usually associated with absolute insulin deficiency
Type 1
Type 1 or 2:
insulin -> lifelong requirement
Type 1
Type 1 or 2:
acute onset: children with type _____ DM seen first in the hospital
type 1
Consider screening patients with Type 1 diabetes for _____ _____ disease and _____ disease soon after diagnosis
autoimmune thyroid
celiac
Type 1 or Type 2:
characterized by insulin resistance (sensitive to insulin) alone or in conjunction with insulin synthesis and secretion
Type 2
Type 1 or Type 2:
slow progressive glucose intolerance/treated initially with diet and exercise/progress to oral hypoglycemic agents to insulin/or both
Type 2
Tabacco use can increase blood sugar levels and lead to…
insulin resistance
The more you smoke, the greater your risk of _____
diabetes
Heavy smokers (> 20 cigarettes a day) almost _____ their risk of developing diabetes
double
Smoking is especially unhealthy for diabetic clients because smoking accelerates the _____ effects that occur in blood vessels from elevated levels of blood glucose.
arteriosclerotic
Type _____ DM rates are greater among youth ages 10-19 with higher rates among US minority populations than in non-hispanic whites
Type 2
T/F: Type 1 diabetes is treated initially with diet and exercise
F, Type 2 is
Gestational Diabetes:
- _____ of all pregnancies
- hormone from the placenta _____ the action of the mother’s insulin
- higher incidence go on to type _____ diabetes later in life (55% within 15 years)
- neonate complications if not _____ (macrosomia: high birth weight, breathing issues etc.)
- 9.2%
- block
- Type 2
controlled
Recommendation to test women with gestational diabetes for persistent diabetes is _____-_____ weeks postpartum to allow the test to be scheduled just before the standard 6-week postpartum check-up so that results an be discussed with pt
4-12 weeks
_____ of US adults aged 20 years or older had _____ (_____ of those aged 65 years or older)
prediabetes (55%)
estimated _____ _____ American aged 20 years or older with prediabetes
86 million
Blood glucose levels higher than normal, but not high enough for a diagnosis of diabetes
prediabetes
Prediabetes: Blood glucose levels higher than normal, but not high enough for a diagnosis of diabetes (_____-_____ FBS)(_____-_____ HgbA1C)
100-128 FBS
5.7-6.4 HgbA1C
other name for prediabetes
impaired fasting glucose or impaired glucose tolerance
Prediabetes is more common in _____ boys and _____-_____ _____ girls
hispanic boys
non-hispanic black girls
Explain Metabolic syndrome: Syndrome X
3 of the 5:
- central obesity
- high BP
- high triglycerides
- low HDL-cholesterol
- insulin resistance
Metabolic syndrome: Syndrome X = at risk for…
heart disease & Type 2 DM
Metabolic syndrome: Syndrome X
3 of the 5:
- central obesity =
Waist measurement:
- men: 40 inches or more
- women: 35 inches or more
Metabolic syndrome: Syndrome X
3 of the 5:
- high BP =
- Systolic: 130 or higher
- Diastolic: 85 or higher
- taking meds for hypertension
Metabolic syndrome: Syndrome X
3 of the 5:
- high triglycerides =
- 150 mg/dL or higher
- taking meds for elevated triglyceride levels
Metabolic syndrome: Syndrome X
3 of the 5:
- low HDL-cholesterol
- men: < 40
- women: < 50
- taking meds for low HDL
Metabolic syndrome: Syndrome X
3 of the 5:
- elevated FBS
- 100 or higher
- taking meds
Lab values for Diabetes:
FBS at or above _____
Prediabetes greater than _____
126 mg/dL
100 mg/dL
Lab values for Diabetes:
2-hour oral glucose tolerance test at or above _____ or random glucose
200 mg/dL