Topical CS

Question 1

TCS increase mitotic activity in the epidermis leading to flattening of basal cell layer and thinning of stratum Corneum and stratum granulosum

Answer 1

False
Decrease mitotic activity
Rest is true

Question 2

TCS promote atrophy of the dermis mostly through inhibition of fibroblast proliferation, migration, chemotaxis and protein synthesis

Answer 2

True

Question 3

Levels of opioid peptides , enkephalins, which modulate epidermal differentiation and inflammatory processes are increased by TCS

Answer 3

False

Reduced

Question 4

Fibroblast synthesis of both glycosaminoycsnd and collagen are inhibited

Answer 4

True

Question 5

TCS induced atrophy feAtures

Answer 5

Lax wrinkly shiny skin with telengiectasiae, purpura, striae, stellate pseudo scars, hypopigmentation, prominent deep vessels

Question 6

TCS penetration around eyelid skin can be 3.6-4x thicker skin eg Palm or sole

Answer 6

F

36-40x

Question 7

TCS reduce synthesis and secretion of cytokines and inflammatory proteins necessary to initiate and sustain an immune response

Answer 7

T