Systemic Antiviral Agents Flashcards
1
Q
Activation of ACV requires phosphorylation by Herpes specific thymidine kinase (TK)
A
T
2
Q
Acyclovir is a guanosine analog which is pregnancy category B
A
True
3
Q
Acyclovir inhibits viral DNA polymerase by serving as an obligate chain terminator in its triphosphorylated form
A
True
4
Q
PAST Q: Oral acyclovir urinary excretion is not affected by probenecid
A
False
5
Q
Past q
Acyclovir safe in pregnancy
A
True
6
Q
Past q
Acyclovir is inactivated by viral thymidine kinase
A
False
7
Q
Past q
Acyclovir is excreted mainly by the kidney
A
False
Roughly equal urine and faecal excretion
8
Q
Past q
Acyclovir is excreted mainly by the kidney
A
False
9
Q
Acyclovir has no hepatic microsomal metabolism
A
True
