PUVA

Question 1

Food slows absorption of psoralens

Answer 1

T

Question 2

Food slows absorption of psoralens

Answer 2

T

Question 3

Psoralens are slowly excreted

Answer 3

F

Question 4

Psoralens are metabolized in liver

Answer 4

T

Question 5

Lactation is a relative CI

Answer 5

False

Absolute

Question 6

Human contact with plants containing psoralens and subsequent exposure to sunlight results in phytophotodermatitis

Answer 6

T

Question 7

There is an extremely low incidence of allergic sensitization to psoralens as they appear significantly in fruits and vegetables

Answer 7

T

Question 8

Pregnancy is an absolute CI

Answer 8

F

Relative

Question 9

When 95% or more of the original area of psoriasis had cleared , patient is changed to a maintenance schedule on PUVA

Answer 9

T

Question 10

Bullous pemphigoid and pemphigoid can be treated with PUVA

Answer 10

F

Absolute CI

Question 11

Need to dose reduce doxy by 25% when using PUVA

Answer 11

T

Question 12

8-MOP is given at a dose of 4mg/kg

Answer 12

F

0.4mg/kg

Question 13

Thiazide diuretics may augment photo toxicity of PUVA

Answer 13

F

Doxycycline and fluoroquinolones

Question 14

Food intake can be used to alleviate problem of nausea when 8-MOP given orally

Answer 14

T

Question 15

MoA of psoralens

Answer 15

Suppress DNA synthesis
Photo immunologic reactions
(Selective immunosuppression)
Selective cytotoxicity
Stimulation of melanocytes

Question 16

Dose reduce doxy and fluoroquinolones with PUVA

Answer 16

T

Question 17

Nausea is an uncommon side effect of 8-MOP

Answer 17

F

Common

Question 18

Photoaging of skin can occur with long term PUVA

Answer 18

T

Question 19

An ophthalmic exam should be obtained close to baseline with PUVA

Answer 19

T

Question 20

Annual ocular exam recommended on PUVA

Answer 20

T

Question 21

PUVA can be used to treat PMLE

NBUVB has PMLE is an AE

Answer 21

T

Question 22

Psoralens are water

Soluble

Answer 22

Insoluble

Question 23

In tx of vitiligo, face is most responsive to PUVA , then trunk then lower limbs

Answer 23

T

Question 24

Eye protection needs to be worn from tint if psoralen exposure until sunset that day

Answer 24

T