PDT Flashcards
ALA requires occlusion
F
ALA is more hydrophilic than MAL
T
Application of ALA does not require occlusion
T
MAL requires premixing before use
False
MAL uses red light
T
MAL is converted to ALA by esterases
T
MAL is available in a cream
T
ALA and MAL are category C
T
When ala is exogenously the control point is bypassed and ala is metabolized along the Haem
Pathway , inducing accumulation of porphyrins (esp protoporphyrin IX)
T
ALA and MAL are highly flourescent
F
As opposed to their precursors MAL and ALA, non metal bound porphyrins are highly fluorescent
Both ALA and MAL PDT are used off label in to of acne
T
Allergy to peanut and almond oil contraindicates use of ALA
F
MAL Cream contains these
MAL is contraindicated in porphyria
T
Sun exposure on treated lesion sites and peripheral skin should be avoided for 24h after topical app of MAL and ALA
F
48h
When ALA-PDT is used on large skin surfaces with shorter application time , photo toxic reaction is more intense
F
Less intense