Topical And I/L antiviral drugs Flashcards
5-FU is incorporated into DNA
F
RNA
5-FU is a purine analog
F
Pyrimidine
5-FU blocks thymidylate reductase
F
Thymidylate synthetase
Bleomycin represents group of sulfur containing glycopeptide cytotoxic antibiotics
T
Bleomycin affects protein synthesis
T
Bleomycin works by binding to HPV
F
Bleomycin acts during the M and G2 phases of the cell cycle by binding to DNA
T
Podophyllin’s most active ingredient and cytodestructive agent is podophyllotoxin
T
How does podophyllotoxin work ?
Binds reversibly to tubulin and arrests cells in metaphase
Podophyllin is not contraindicated in pregnancy
F
Trichloroacetic acid works by causing hydrolysis of cellular proteins leading to inflammation and cell death
T
Cantharadin has direct viral effect
F