Topic 32 Flashcards
What do population genetics and quantitative genetics both focus on?
The genetic basis of phenotypic variation among the individuals in a population
What does population genetics usually deal with?
It ususally deals with frequencies of alleles and genotypes
What does quantitative genetics concentrate on?
It concentrates on the ways that individual variation in genotype and environment contribute to variance in phenotype
Why are gene environment interactions studied?
To gain a better understanding of various phenomena
What is gene environment interactions useful for in genetic epidemiology?
They’re useful for understanding some diseases
Is the disease itself always inherited?
Sometimes, sensitivity to environmental risk factors for a disease are inherited rather than the disease itself being inherited
What can gene environment interactions result in?
Different disease phenotypes
Why does gene environment interactions result in different disease phenotypes?
Individuals with different genotypes are affected differently by exposure to the same environment factors e.g. sunlight exposure has a stronger influence on skin cancer risk in fair skinned than in dark skinned
V phenotype=
v genetic + v environment
V environment =
v temporary + v permanent
personalized medicine
a medical model that separates people into different groups—with medical decisions, practices, interventions and/or products being tailored to the individual patient based on their predicted response or risk of disease
