Topic 12

Question 1

prolificacy

Answer 1

high fertility, a lot of offspring

- sheep and swine only

Question 2

FecB gene

Answer 2

Autosomal inheritance on 6th chromosome

Codes for BMPR-1B (bone morphogenic protein receptor)

In hetero- and homozygotes: decrease inhibition of 17-B estradiol secretion in granulose cells during follicle growth and maturation = polyovulation, multiple births and increased litter sizes

Selective FHS modulator

Extra effect in homozygotes

Dominant and positive dose effect: homozygotes have higher litter sizes etc

Question 3

FecX gene

Answer 3

X-linked inheritance
BMP-15

Effect only in heterozygotes: plyovulation, multiple births

Dominant and effect in homozygotes: homozygotes become sterile and unfertile