Therapeutics 1 - Increased Intestinal Permeability Flashcards
Q: What is increased intestinal permeability also known as?
A: Increased intestinal permeability is commonly known as leaky gut syndrome.
Q: What happens in leaky gut syndrome?
A: Damage to the mucosal barrier (tight junctions) of the intestines allows bacterial cell walls and undigested food particles to enter the bloodstream.
Q: List some conditions associated with leaky gut syndrome.
A: Conditions include allergies, eczema, arthritis, irritable bowel syndrome (IBS), autoimmunity, and inflammatory bowel disease (IBD).
Q: What are some causes of increased intestinal permeability?
A: Causes include poor nutrition (trans fats, refined sugars, wheat), toxic substances (NSAIDs, alcohol, pesticides), gut wall inflammation (dysbiosis, yeast, parasites), and emotional stress.
Q: How does emotional stress affect the gut?
A: Emotional stress can alter gut pH, contributing to gut dysfunction and increased permeability.
Q: What nutritional support is recommended for healing the mucosal barrier?
Glutamine: 10 grams per day; found in cabbage juice, spirulina, asparagus, broccoli, cod, and salmon.
N-acetyl Glucosamine: Found in shellfish; supports mucosal integrity.
Quercetin: Found in apples, red onions, tomatoes, and red peppers; has anti-inflammatory properties.
Q: What herbal remedies are beneficial for increased intestinal permeability?
Slippery Elm or Marshmallow Root: Mix 1 tsp of powder in warm water, drink three times daily between meals.
Liquorice and Calendula Tea: Provides soothing effects on the gut lining.
Q: What is the role of bone broth in gut healing?
A: Bone broth is rich in collagen, glucosamine, and chondroitin, which are beneficial for healing the gut lining.
Q: How can a comprehensive stool test help in diagnosing increased intestinal permeability?
A: It can identify underlying causes of permeability, including markers for inflammation, dysbiosis, and gut microbiota composition.
Q: What is the difference between normal tight junctions and leaky gut?
Normal Tight Junctions: Healthy intestinal barrier that prevents harmful substances from passing through.
Leaky Gut: Damage to tight junctions allows bacteria and undigested food particles to leak into the bloodstream.
Q: What is zonulin, and how does it relate to intestinal permeability?
A: Zonulin is a human protein that can cause increased intestinal permeability by disassembling tight junctions. Elevated levels indicate dysfunction in the intestinal barrier.
