Detoxification 2 - The Liver Flashcards
Q: What is the primary organ responsible for detoxification in the body?
A: The liver.
Q: What percentage of toxins can the liver clear from the blood?
A: Up to 99%.
Q: Name three factors that can impair liver function.
A: Alcohol, excess fats (saturated, trans, hydrogenated), and drugs (prescription, OTC, recreational).
Q: List three symptoms of reduced liver detoxification.
A: Skin issues (acne, eczema), digestive problems (nausea, constipation), and fatigue.
Q: How does poor liver function affect emotions according to traditional systems?
A: It can lead to anger and irritability.
Q: Name three herbs that support liver function.
A: Dandelion root, milk thistle, and schisandra.
Q: What is the Cytochrome P450 system?
A: A collection of enzymes involved in Phase 1 detoxification that converts toxins into smaller, water-soluble forms.
Q: Why is antioxidant intake important during Phase 1 detoxification?
A: To neutralize free radicals generated during the detoxification process.
Q: What are some substances that impair Phase 1 liver detoxification?
A: Excess alcohol, caffeine, organophosphates, barbiturates, and heavy metals.
Q: Which vitamins are crucial for Phase 1 detox enzyme function?
A: B vitamins (B1, B2, B3, B6, B9, B12), and antioxidants like vitamins C and E.
Q: What happens in Phase 2 liver detoxification?
A: Toxins are conjugated, making them water-soluble for excretion via urine or bile.
Q: Which antioxidant plays a key role in Phase 2 detoxification?
A: Glutathione.
Q: Name a factor that impairs Phase 2 detoxification.
A: Nutrient deficiencies, aging, or underactivity of liver cell mitochondria.
Q: List three supplements that support Phase 2 detoxification.
A: Milk thistle, N-Acetyl-Cysteine (NAC), and turmeric.
Q: What is glucuronidation, and what inhibits it?
A: A Phase 2 detox pathway that detoxifies substances like estrogens and NSAIDs. It is inhibited by aspirin and fluoride.
