Terminal Respiration Flashcards

1
Q

Mitochondria is the only place that ___ can occur

A

Oxidative phosphorylation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is required to be in mitochondrial matrix for terminal respiration

A

NADH and FADH2 (formed there by citric acid cycle and beta oxidation of fatty acids)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Glycerol phosphate shuttle

A

Dihydroxy acetone phosphate is converted into glycerol 3 phosphate so that G3P can cross the mitochondrial membrane and pass electrons from NADH to FADH2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What cannot cross the membrane of mitochondria

A

NADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What creates more atp FADH2 or NADH

A

NADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What do the different complexes involved in electron transport chain do

A

Link the passing of the electrons from inside of the mitochondria to the inter membrane space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Complex 1 of electron transport chain

A

Oxidises NADH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Complex II

A

Oxidises FADH2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Complex III

A

Takes electrons from ubiquinol and passes to cytochrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Complex IV

A

Takes electrons from cytochrome c and passes them to molecular oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How is energy conserved through the electron transport chain

A

Proton gradient across the inner mitochondrial membrane and oxidation of NADH FADH2 ubiquionine and cytochrome c

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How is the energy that is stored in the H+ gradient used?

A
  • electron motive force (proton)

- molecular turbine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Chemiosmosis

A

Electrons pass through the complex of the transport chain as protons move from the matrix to outside of inner mitochondrial membrane.
Vectoral
Energy transformation
Release energy as it is down conc gradient. Proton motive force

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ATP synthesis uses what enzyme

A

ATP synthase, allows protons to pass through and uses energy released from down conc gradient to combine ADP and Pi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Two parts of ATP synthase

A

F0 and F1- where it occurs. Rotation of F0 cylinder forces conformational changes in the beta subunits of F1 this conformational change catalyses ADP into ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Stoichiometrically, how many moles of ATP are generated per mol of NADH and FADH2

A

2.5 mols and 1.5 mols

17
Q

Where can protons cross the electron transport chain

A

Complex 1, III, IV

18
Q

How many ATP can be made per every 3 H+ moved by ATP synthase

A

One per every 3

19
Q

How many H+s are crossed from matrix to the outside of the membrane

A

8

20
Q

What happens to the energy released from electrons if ATP synthase and electron transport chain is uncoupled

A

Does not make ATP as the proton gradient cannot be generated so it is released as heat eg malignant hypothermia, or cold babies