Drug interactions Flashcards
what is drug interaction
modification of a drugs effect by prior or concomitant administration of another drug, herb, foodstuff, drink
what is drug interaction
modification of a drugs effect by prior or concomitant administration of another drug, herb, foodstuff, drink
drug precipitants
food, drink, smoking, alcohol, drugs,
which illnesses use drug-drug interactions
hypertension, ischaemic heart disease, Parkinsonism
what factors may predispose a patient to drug interactions
drugs with steep dose response curve, narrow therapeutic index, high protein binding, hepatic enzyme inducers or inhibitors, and those that alter renal clearance
drug precipitants
food, drink, smoking, alcohol, drugs,
which illnesses use drug-drug interactions
hypertension, ischaemic heart disease, Parkinsonism
what is the medical importance of drug interactions
can cause morbidity and
mortality
what factors may predispose a patient to drug interactions
drugs with steep dose response curve, narrow therapeutic index, high protein binding, hepatic enzyme inducers or inhibitors, and those that alter renal clearance. also self subscription, multiple doctors, advanced age
what are drug - drug interactions.
mixing two drugs in the same solution causing pharmaceutical interactions which can alter the absorption, distribution or elimination of a drug. can be direct or indirect
why is it important to monitor therapeutic drug
to ensure that the amount of certain medicines in your blood is safe and effective