Drug delivery systems Flashcards

1
Q

factors which affect the bioavailability of a drug

A

dose of drug, frequency of administration, timing of administration, desired speed of onset

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2
Q

strengths of the different routes of administration via the GI tract.

A

good for patients unable to swallow, treat local conditions, bypass pre systemic metabolism,

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3
Q

strengths of different preparation forms suitable for oral administration.

A

solutions are easily absorbed, suspensions are good for drugs that are unpalatable, buccal and sublingual good for drugs with extensive pre systemic or first pass metabolism. tablets are convenient, accurate, easy to produce, enteric coating protects drug from acid and stomach from drug

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4
Q

the strengths with examples, of locally administered

medication (topical, inhaled).

A

drug delivered to site of action, rapid effect, small doses used, reduced adverse effect

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5
Q

prodrugs

A

inactive derivatives of active drug which needs metabolically activated after administration. avoids degradation in gut

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6
Q

weaknesses, with examples, of locally administered

medication (topical, inhaled).

A

patient eduction is essential

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