Nitrogen Flashcards
What do amino acids and nucleotides contain that carbohydrates and fats do not
Nitrogen
What is phenylketonuria
When there is an absence of phenylalanine hydroxylase so there is a build up of phenylalanine and a deficiency of tyrosine. This creates phenyl ketones that spill over. Some of these products cross blood brain barrier and cause irreversible damage to brain
Ammonia is produced by
Break down of amino acids NH4
What does urea cycle do
Takes ammonia and converts it into urea and excretes it in Urine. Way of detoxifying ammonia
what are essential amino acids
cannot be synthesised by body so need to be consumed
how is nitrogen transferred between amino acids
by oxidative deamination and transamination reactions
glutamine
protein that is transported through plasma to liver
alanine
protein that is transported to liver from skeletal muscle
what does transport of alanine provide
safe movement of carbon from pyruvate for regeneration of glucose
glutamate
nitrogen fixes to glutamate and flows to other biomolecules. only amino acid that can obtain nitrogen directly from ammonium ions,
what point does urea get produced in the cycle
between arganine and ornithine