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DRUG OF THE DAY > Sodium Valproate > Flashcards

Sodium Valproate Flashcards

1
Q

Drug Class

A

Anti-Epileptic Drugs

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2
Q

Common Indications

A

all forms of epilepsy

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3
Q

Mechanism of Action

A

sodium channel blockade & GABAa effects

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4
Q

Adverse Effects

A

liver failure
pancreatitis
lethargy
(nausea, mood changes, osteoporosis, BM failure for all AEDs)

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5
Q

Contraindications

A

risk of congenital malformations

so only given to women of childbearing age if meet conditions of pregnancy prevention programme

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7
Q

Drug Interactions

A

only CYP inhibitor of AEDs (warfarin)
alcohol
can increase plasma conc of other AEDs

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DRUG OF THE DAY (27 decks)

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